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Synaptic Mechanisms of Continuous Theta Burst Stimulation in Depression

NCT07560878

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

Many people with depression do not get better with standard treatments like medication. One promising alternative is transcranial magnetic stimulation (TMS), a non-invasive procedure that uses magnetic pulses to stimulate specific brain regions. A particular pattern of TMS called continuous theta-burst stimulation (cTBS) is thought to reduce overactive brain activity in depression, but the investigators do not yet fully understand how it works at the level of brain cells and connections.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Major Depression

Eligibility basics and study details

Study type
Interventional
Phase
Early Phase 1
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
Mclean Hospital
Last updated on ClinicalTrials.gov
May 13, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Massachusetts · 1

  • McLean Hospital · Belmont, MA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.