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Phase 1 Study of PF-08046033 in Advanced Solid Tumors

NCT07519655

This study is recruiting at 11 US sites in 4 states, according to its ClinicalTrials.gov record last updated .

Summary

This is an early-stage (Phase 1) clinical study testing a new study medicine called PF-08046033. The goal of the study is to understand how safe the medicine is, how well people tolerate it, how it behaves in the body, and whether it shows early signs of helping to treat cancer. The study includes adult participants who have advanced cancers that cannot be removed by surgery or have spread to other parts of the body. These cancers include non-small cell lung cancer, esophageal squamous cell cancer, and melanoma.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Non-Small-Cell Lung
  • Esophageal Cancer
  • Cutaneous Melanoma

Eligibility basics and study details

Study type
Interventional
Phase
Phase 1
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
Pfizer
Last updated on ClinicalTrials.gov
October 13, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Colorado · 2

  • Presbyterian/St Lukes Medical Center · Denver, CO
  • Sarah Cannon Research Institute at HealthONE · Denver, CO

Connecticut · 5

  • Smilow Cancer Hospital - Yale New Haven Health · New Haven, CT
  • Smilow Cancer Hospital Phase 1 Unit · New Haven, CT
  • Yale - New Haven Hospital - Yale Cancer Center · New Haven, CT
  • Yale University - Smilow Cancer Hospital; C/O Thomas Ferencz, RPh, BCOP · New Haven, CT
  • Smilow Cancer Hospital - Trumbull · Trumbull, CT

Tennessee · 2

  • Sarah Cannon Research Institute- Pharmacy · Nashville, TN
  • SCRI Oncology Partners · Nashville, TN

Virginia · 2

  • Inova Schar Cancer · Fairfax, VA
  • Inova Schar Cancer Infusion Pharmacy · Fairfax, VA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.