A Study to Evaluate Efficacy and Safety of MK-8690 in Participants With Moderately to Severely Active Ulcerative Colitis (MK-8690-002)
NCT07463183
This study is recruiting at 11 US sites in 7 states, according to its ClinicalTrials.gov record last updated .
Summary
The purpose of this protocol is to evaluate the efficacy of MK-8690 in participants with moderately to severely active ulcerative colitis. The primary hypothesis is that MK-8690 is superior to placebo with respect to the proportion of participants achieving clinical remission per Modified Mayo Score at Week 12.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Colitis Ulcerative
- Ulcerative Colitis
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 2
- Ages
- 18 to 75 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Merck Sharp & Dohme LLC
- Last updated on ClinicalTrials.gov
- September 28, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
California · 2
- Clinnova Research ( Site 1042) · Anaheim, CA
- Southern California Research Center ( Site 1044) · Coronado, CA
Colorado · 2
- Peak Gastroenterology Associates ( Site 1052) · Colorado Springs, CO
- South Denver Gastroenterology, PC ( Site 1068) · Englewood, CO
Florida · 3
- Nature Coast Clinical Research ( Site 1045) · Inverness, FL
- Research Associates of South Florida - Miami - Southwest 8th Street ( Site 1072) · Miami, FL
- AdventHealth Orlando ( Site 1074) · Orlando, FL
Georgia · 1
- Gastroenterology Associates of Central Georgia ( Site 1060) · Macon, GA
Kansas · 1
- University of Kansas Medical Center ( Site 1077) · Kansas City, KS
Louisiana · 1
- Tulane University School of Medicine-Gastroenterology and Hepatology ( Site 1073) · New Orleans, LA
Missouri · 1
- BVL Research - Kansas ( Site 1054) · Liberty, MO
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.