LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
NCT07415044
This study is recruiting at 39 US sites in 21 states, according to its ClinicalTrials.gov record last updated .
Summary
The main purpose of this study is to evaluate the safety and effectiveness of LY4268989 when compared to placebo in adult participants with moderately to severely active ulcerative colitis (UC). The study drug will be administered orally. The study will last up to approximately 108 weeks, excluding screening.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Ulcerative Colitis (UC)
- Ulcerative Colitis, Active Moderate
- Ulcerative Colitis, Active Severe
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 2
- Ages
- 18 to 80 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Eli Lilly and Company
- Last updated on ClinicalTrials.gov
- October 8, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Arizona · 1
- Valleywise Health Medical Center · Phoenix, AZ
California · 4
- Clinnova Research · Anaheim, CA
- GMC Clinical Research · Folsom, CA
- Om Research LLC · Temple City, CA
- Om Research LLC · Victorville, CA
Colorado · 2
- Peak Gastroenterology Associates · Colorado Springs, CO
- Rocky Mountain Gastroenterology Associates - Lakewood · Lakewood, CO
Florida · 3
- K2 Medical Research - Daytona Beach · Daytona Beach, FL
- Clinical Research of Osceola · Kissimmee, FL
- Florida Research Institute · Lakewood Rch, FL
Idaho · 2
- Treasure Valley Medical Research · Boise, ID
- Grand Teton Research Group · Idaho Falls, ID
Illinois · 2
- Midwest Digestive Health & Nutrition · Des Plaines, IL
- Springfield Clinic - First · Springfield, IL
Indiana · 1
- Gastroenterology Health Partners · New Albany, IN
Kentucky · 1
- Gastroenterology Health Partners · Louisville, KY
Louisiana · 1
- GI Alliance - Gastro Group and Endocenter - Mandeville · Mandeville, LA
Michigan · 1
- Gastroenterology Associates of Western Michigan, PLC d.b.a. West Michigan Clinical Research Center · Wyoming, MI
Missouri · 2
- KAD Clinical Research · St Louis, MO
- Specialists in Gastroenterology · St Louis, MO
Nevada · 1
- Digestive Disease Specialists - Las Vegas - Crimson Canyon Drive · Las Vegas, NV
New Jersey · 1
- Saint Peter's University Hospital · New Brunswick, NJ
North Carolina · 2
- Carolina Digestive Diseases and Endoscopy Center · Greenville, NC
- Wilmington Health, PLLC · Wilmington, NC
Ohio · 2
- DSI Research, LLC d/b/a ObjectiveHealth Clinical Research - Springboro · Springboro, OH
- Gastro Intestinal Research Institute of Northern Ohio, LLC · Westlake, OH
Oregon · 1
- The Oregon Clinic · Portland, OR
South Dakota · 1
- Sanford USD Medical Center · Sioux Falls, SD
Tennessee · 1
- Skyline Gastroenterology of West Tennessee · Jackson, TN
Texas · 7
- GI Alliance - Fort Worth · Fort Worth, TX
- GI Alliance - Garland · Garland, TX
- Integrity Advanced Therapeutics · Houston, TX
- GI Alliance: Mansfield · Mansfield, TX
- Southern Star Research Institute · San Antonio, TX
- GI Alliance - San Marcos · San Marcos, TX
- Tyler Research Institute · Tyler, TX
Virginia · 1
- Eximia Research-VA, LLC · Norfolk, VA
Washington · 2
- Principle Research Solutions · Spokane, WA
- Washington Gastroenterology - Tacoma · Tacoma, WA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.