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A Study of YL201 in Combination With Other Anti-Cancer Therapies in Patients With Advanced Solid Tumors

NCT07407933

This study is recruiting at 5 US sites in 5 states, according to its ClinicalTrials.gov record last updated .

Summary

This is a phase Ib/II, multicenter, open-label study of YL201 combined with atezolizumab. The study will include 2 parts. Part 1 of the study is a dose escalation in participants with previously untreated ES-SCLC to determine the safety and tolerability of YL201 in combination with fixed dose of atezolizumab. The planned dose levels of YL201 are 1.2 mg/kg, 1.6 mg/kg and 2.0 mg/kg. Part 2 consists of a dose optimization stage followed by a dose expansion stage.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Thoracic Neoplasms, Lung Diseases, Small Cell Lung Carcinoma

Eligibility basics and study details

Study type
Interventional
Phase
Phase 1/2
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
MediLink Therapeutics (Suzhou) Co., Ltd.
Last updated on ClinicalTrials.gov
September 17, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

District of Columbia · 1

  • Site 1001 · Washington D.C., DC

Florida · 1

  • Site 1009 · Plantation, FL

Kentucky · 1

  • Site 1004 · Louisville, KY

Texas · 1

  • Site 1005 · Houston, TX

Virginia · 1

  • Site 1002 · Fairfax, VA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.