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Addition of Venetoclax to Combined Hematopoietic Stem Cell and Kidney Transplantation

NCT07358195

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

The primary objective is to assess the safety of the addition of venetoclax to reduced intensity conditioning for HLA-matched and haploidentical combined HSC and kidney transplantation as measured by stable full donor hematopoiesis and absence of CTCAE grade IV or V toxicity attributable to venetoclax.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Kidney Failure Chronic
  • Stem Cell Transplant
  • Stem Cell Transplant Complications
  • Tolerance
  • Hematologic Cancer

Eligibility basics and study details

Study type
Interventional
Phase
Early Phase 1
Ages
18 to 70 years
Sex
All
Healthy volunteers
Not accepted
Sponsor
Massachusetts General Hospital
Last updated on ClinicalTrials.gov
October 14, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Massachusetts · 1

  • Massachusetts General Hospital · Boston, MA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.