A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2)
NCT07355218
This study is recruiting at 14 US sites in 7 states, according to its ClinicalTrials.gov record last updated .
Summary
The purpose of this global, multicenter, Phase 3 study is to evaluate the efficacy and safety of enpatoran over 24 weeks in participants with active cutaneous manifestations of lupus erythematosus with or without systemic disease. Study details include: Study Duration: Up to 35 weeks. Treatment Duration: 24 weeks. Visit Frequency: every 4 weeks, with the exception of the Week 2 televisit. Study Intervention Name: Enpatoran, Placebo. Intervention Form: Film-coated tablet.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Systematic Lupus Erythematosus
- Cutaneous Lupus Erythematosus
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 3
- Ages
- 18 to 75 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- EMD Serono Research & Development Institute, Inc.
- Last updated on ClinicalTrials.gov
- October 6, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
California · 1
- Inland Rheumatology Clinical Trials, Inc. · Upland, CA
Florida · 6
- Omega Research Debary, LLC · DeBary, FL
- Centre for Rheumatology, Immunology and Arthritis · Fort Lauderdale, FL
- South Florida Rheumatology · Hollywood, FL
- GTL Medical And Research Group · Miami, FL
- Bolanos Clinical Research · Pembroke Pines, FL
- Vantage Clinical Trials · Tampa, FL
Indiana · 1
- Dawes Fretzin Clinical Research Group, LLC · Indianapolis, IN
Louisiana · 1
- Accurate Clinical Research Inc. - Lake Charles · Lake Charles, LA
Michigan · 1
- Oakland Hills Dermatology · Auburn Hills, MI
North Carolina · 2
- Arthritis and Osteoporosis Consultants of the Carolinas II, LLC · Charlotte, NC
- Superior Clinical Research, LLC · Smithfield, NC
Texas · 2
- North Texas Center for Clinical Research · Frisco, TX
- Accurate Clinical Research · Humble, TX
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.