Endotype DIrected Treatment for OSA in Down Syndrome
NCT07280468
This study is recruiting at 5 US sites in 5 states, according to its ClinicalTrials.gov record last updated .
Summary
Down syndrome is the most common genetic cause of intellectual disability. People with Down syndrome often have obstructive sleep apnea (OSA), a condition where people have difficulties with breathing while asleep. OSA can lead to poor sleep, worse quality of life, behavior problems and more difficulties with thinking ("cognitive impairment"). Current treatments for OSA in people with Down syndrome are not very effective or require surgery.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Obstructive Sleep Apnea (OSA)
- Down Syndrome
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 4
- Ages
- 6 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- University of Arizona
- Last updated on ClinicalTrials.gov
- September 3, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Arizona · 1
- University of Arizona · Tucson, AZ
California · 1
- University of California San Diego · San Diego, CA
Florida · 1
- University of Miami · Miami, FL
Illinois · 1
- Advocate Medical Group Adult Down Syndrome Center · Park Ridge, IL
Pennsylvania · 1
- Children's Hospital of Philadelphia · Philadelphia, PA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.