Symbiotic-Lung-04: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Extensive-Stage Small Cell Lung Cancer
NCT07226999
This study is recruiting at 54 US sites in 5 states, according to its ClinicalTrials.gov record last updated .
Summary
This study is being done to learn more about a new medicine called PF-08634404 and how well it works when given with chemotherapy to adults with extensive-stage small cell lung cancer (ES-SCLC), a fast-growing type of lung cancer that has spread widely in the body. To join the study, participants must meet the following conditions: Be 18 years or older. Have extensive-stage small cell lung cancer confirmed by lab tests. Have not received chemotherapy or radiation for this type of lung cancer. Be in good physical condition and have healthy organs based on medical tests.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Small Cell Lung Cancer (SCLC)
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 2/3
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Pfizer
- Last updated on ClinicalTrials.gov
- October 8, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Arkansas · 3
- Highlands Oncology Group · Fayetteville, AR
- Highlands Oncology Group · Rogers, AR
- Highlands Oncology Group · Springdale, AR
Florida · 3
- BRCR Coral Springs · Coral Springs, FL
- Mid Florida Hematology and Oncology Center · Orange City, FL
- BRCR Global - Tamarac · Tamarac, FL
Ohio · 1
- University Hospitals Cleveland Medical Center · Cleveland, OH
Texas · 36
- Texas Oncology - Northeast Texas · Allen, TX
- Texas Oncology - DFW · Arlington, TX
- Texas Oncology - DFW · Arlington, TX
- Texas Oncology - Gulf Coast · Beaumont, TX
- Texas Oncology - DFW · Bedford, TX
- Texas Oncology - DFW · Dallas, TX
- Texas Oncology - DFW · Dallas, TX
- Texas Oncology - DFW · Dallas, TX
- Texas Oncology - DFW · Dallas, TX
- Texas Oncology - DFW · Dallas, TX
- Texas Oncology - Northeast Texas · Denison, TX
- Texas Oncology - Northeast Texas · Denton, TX
- Texas Oncology - Northeast Texas · Flower Mound, TX
- Texas Oncology - DFW · Fort Worth, TX
- Texas Oncology - San Antonio · Fredericksburg, TX
- Texas Oncology - DFW · Grapevine, TX
- Texas Oncology - Gulf Coast · Houston, TX
- Texas Oncology - Gulf Coast · Houston, TX
- US Oncology Investigational Product Center (IPC) · Irving, TX
- US Oncology Investigational Products Center (IPC) · Irving, TX
- Texas Oncology - Northeast Texas · Lewisville, TX
- Texas Oncology - Northeast Texas · Longview, TX
- Texas Oncology - Northeast Texas · McKinney, TX
- Texas Oncology - San Antonio · New Braunfels, TX
- Texas Oncology - Northeast Texas · Palestine, TX
- Texas Oncology - Northeast Texas · Paris, TX
- Texas Oncology - Gulf Coast · Pearland, TX
- Texas Oncology - DFW · Plano, TX
- Texas Oncology - DFW · Plano, TX
- Texas Oncology - San Antonio · San Antonio, TX
- Texas Oncology - San Antonio · San Antonio, TX
- Texas Oncology - San Antonio · San Antonio, TX
- Texas Oncology - Gulf Coast · Sugar Land, TX
- Texas Oncology - Gulf Coast · The Woodlands, TX
- Texas Oncology - Northeast Texas · Tyler, TX
- Texas Oncology - Gulf Coast · Webster, TX
Virginia · 11
- Oncology & Hematology Associates of Southwest Virginia, Inc., DBA Blue Ridge Cancer Care · Blacksburg, VA
- Virginia Oncology Associates · Chesapeake, VA
- Virginia Oncology Associates · Hampton, VA
- Oncology & Hematology Associates of Southwest Virginia, Inc., DBA Blue Ridge Cancer Care · Low Moor, VA
- Virginia Oncology Associates · Newport News, VA
- Virginia Oncology Associates · Norfolk, VA
- Oncology & Hematology Associates of Southwest Virginia, Inc., DBA Blue Ridge Cancer Care · Roanoke, VA
- Oncology & Hematology Associates of Southwest Virginia, Inc., DBA Blue Ridge Cancer Care · Salem, VA
- Virginia Oncology Associates · Virginia Beach, VA
- Virginia Oncology Associates · Williamsburg, VA
- Oncology & Hematology Associates of Southwest Virginia, Inc., DBA Blue Ridge Cancer Care · Wytheville, VA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.