A Pivotal Clinical Study to Investigate Efimosfermin Alfa in Participants With Biopsy-confirmed F2- or F3-stage MASH
NCT07221227
This study is recruiting at 76 US sites in 18 states, according to its ClinicalTrials.gov record last updated .
Summary
The purpose of this study is to assess the safety and efficacy of efimosfermin alfa in the resolution of steatohepatitis and improvement of liver-related clinical outcome compared to placebo in individuals with MASH and biopsy-confirmed F2- or F3-stage fibrosis.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Non-alcoholic Fatty Liver Disease
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 3
- Ages
- 18 to 75 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- GlaxoSmithKline
- Last updated on ClinicalTrials.gov
- July 27, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Arizona · 2
- GSK Investigational Site · Chandler, AZ
- GSK Investigational Site · Tucson, AZ
Arkansas · 1
- GSK Investigational Site · Little Rock, AR
California · 9
- GSK Investigational Site · Arcadia, CA
- GSK Investigational Site · Covina, CA
- GSK Investigational Site · Folsom, CA
- GSK Investigational Site · Los Angeles, CA
- GSK Investigational Site · Montclair, CA
- GSK Investigational Site · Riverdale, CA
- GSK Investigational Site · San Diego, CA
- GSK Investigational Site · Santa Maria, CA
- GSK Investigational Site · Van Nuys, CA
Colorado · 1
- GSK Investigational Site · Colorado Springs, CO
Florida · 23
- GSK Investigational Site · Boynton Beach, FL
- GSK Investigational Site · Cape Coral, FL
- GSK Investigational Site · Clermont, FL
- GSK Investigational Site · Fort Myers, FL
- GSK Investigational Site · Hialeah, FL
- GSK Investigational Site · Hialeah, FL
- GSK Investigational Site · Homestead, FL
- GSK Investigational Site · Inverness, FL
- GSK Investigational Site · Jacksonville, FL
- GSK Investigational Site · Kissimmee, FL
- GSK Investigational Site · Lakeland, FL
- GSK Investigational Site · Maitland, FL
- GSK Investigational Site · Miami, FL
- GSK Investigational Site · Miami, FL
- GSK Investigational Site · Miami, FL
- GSK Investigational Site · Miami, FL
- GSK Investigational Site · Miami, FL
- GSK Investigational Site · Miami, FL
- GSK Investigational Site · Miami, FL
- GSK Investigational Site · Miami Lakes, FL
- GSK Investigational Site · Ocala, FL
- GSK Investigational Site · Palmetto Bay, FL
- GSK Investigational Site · Sarasota, FL
Georgia · 1
- GSK Investigational Site · Marietta, GA
Kansas · 1
- GSK Investigational Site · Topeka, KS
Louisiana · 2
- GSK Investigational Site · Bastrop, LA
- GSK Investigational Site · Marrero, LA
Missouri · 3
- GSK Investigational Site · Kansas City, MO
- GSK Investigational Site · Springfield, MO
- GSK Investigational Site · St Louis, MO
Nevada · 1
- GSK Investigational Site · Las Vegas, NV
New York · 3
- GSK Investigational Site · East Syracuse, NY
- GSK Investigational Site · New York, NY
- GSK Investigational Site · New York, NY
North Carolina · 2
- GSK Investigational Site · Fayetteville, NC
- GSK Investigational Site · Morehead City, NC
Ohio · 3
- GSK Investigational Site · Akron, OH
- GSK Investigational Site · Springboro, OH
- GSK Investigational Site · Westlake, OH
Tennessee · 1
- GSK Investigational Site · Chattanooga, TN
Texas · 19
- GSK Investigational Site · Arlington, TX
- GSK Investigational Site · Austin, TX
- GSK Investigational Site · Austin, TX
- GSK Investigational Site · Austin, TX
- GSK Investigational Site · Bellaire, TX
- GSK Investigational Site · Brownsville, TX
- GSK Investigational Site · Dallas, TX
- GSK Investigational Site · DeSoto, TX
- GSK Investigational Site · Houston, TX
- GSK Investigational Site · Irving, TX
- GSK Investigational Site · Richmond, TX
- GSK Investigational Site · San Antonio, TX
- GSK Investigational Site · San Antonio, TX
- GSK Investigational Site · San Antonio, TX
- GSK Investigational Site · Seabrook, TX
- GSK Investigational Site · Sugar Land, TX
- GSK Investigational Site · Tomball, TX
- GSK Investigational Site · Waco, TX
- GSK Investigational Site · Waco, TX
Utah · 1
- GSK Investigational Site · West Jordan, UT
Virginia · 2
- GSK Investigational Site · Manassas, VA
- GSK Investigational Site · Norfolk, VA
Washington · 1
- GSK Investigational Site · Seattle, WA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.