A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio
NCT07215390
This study is recruiting at 78 US sites in 24 states, according to its ClinicalTrials.gov record last updated .
Summary
A Phase 2, Randomized, Placebo-controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL-3007 in Combination with Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed with Geographic Atrophy Secondary to Age-Related Macular Degeneration
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Geographic Atrophy Secondary to Age-related Macular Degeneration
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 2
- Ages
- 60 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Apellis Pharmaceuticals, Inc.
- Last updated on ClinicalTrials.gov
- June 24, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Arizona · 5
- Associated Retina Consultants (01065) · Gilbert, AZ
- Barnet Dulaney Perkins Eye Center (01018) · Mesa, AZ
- Associated Retina Consultants - Phoenix · Phoenix, AZ
- Retinal Research Institute, LLC (01021) · Phoenix, AZ
- Research Network Arizona · Scottsdale, AZ
California · 11
- California Retina Consultants (CRC) - Bakersfield Office · Bakersfield, CA
- Retinal Diagnostic Center · Campbell, CA
- The Retina Partners - Encino · Encino, CA
- Retina Consultants of Orange County - Fullerton Office · Fullerton, CA
- Salehi Retina Institute, Inc dba Retina Associate or Southern California (01034) · Huntington Beach, CA
- Salehi Retina Institute, Inc. Dba Retina Associates of Southern California (01034) · Huntington Beach, CA
- California Retina Consultants (01054) · Oxnard, CA
- Retina Consultants San Diego · Poway, CA
- Orange County Retina Medical Group · Santa Ana, CA
- Retina Macula Institute · Torrance, CA
- Bay Area Retina Associates - Walnut Creek · Walnut Creek, CA
Colorado · 2
- Colorado Retina Associates, PLLC · Lakewood, CO
- Advanced Vision Research Institute · Longmont, CO
Connecticut · 1
- Connecticut Eye Consultants, PC (01074) · Danbury, CT
Florida · 9
- ClearVista Clinical Research, LLC (01096) · Bayonet Point, FL
- Advance Retina Institute · Bonita Springs, FL
- Florida Retina Institute - Orlando (01053) · Orlando, FL
- Florida Retina Institute (01053) · Orlando, FL
- Retina Specialty Institute - Pensacola · Pensacola, FL
- Eye Associates of Pinellas (01020) · Pinellas Park, FL
- Retina Vitreous Associates of Florida (RVA) - Saint Petersburg · St. Petersburg, FL
- Retina Vitreous Associates of Florida · Tampa, FL
- Center for Retina and Macular Disease (01026) · Winter Haven, FL
Georgia · 1
- Southeast Retina Center · Augusta, GA
Illinois · 1
- Illinois Retina Associates, S.C. - Oak Park (01061) · Oak Park, IL
Indiana · 4
- Midwest Eye Institute (01066) · Carmel, IN
- Advancing Research International. LLC (01090) · Indianapolis, IN
- Retina Consultants P.C. · Indianapolis, IN
- Vision Research Solutions · Indianapolis, IN
Louisiana · 1
- Retina Associates New Orleans - Jefferson Parish Location · Metairie, LA
Maryland · 4
- The Retina Care Center · Baltimore, MD
- The Retina Group of Washington (01089) · Chevy Chase, MD
- Cumberland Valley Retina Consultants (CVRC) · Hagerstown, MD
- Retina Specialists · Towson, MD
Mississippi · 1
- Mississippi Retina Associates · Madison, MS
New Jersey · 4
- Envision Ocular, LLC (01027) · Bloomfield, NJ
- Mid Atlantic Retina (01039) · Cherry Hill, NJ
- NJ Retina (01031) · Edison, NJ
- NJ Retina (01030) · Toms River, NJ
New Mexico · 1
- Vision Research Center Eye Associates of New Mexico (01023) · Albuquerque, NM
New York · 2
- Long Island Vitreoretinal Consultants (01050) · Great Neck, NY
- Long Island Vitreoretinal Consultants - Westbury · Long Island City, NY
Ohio · 2
- Retina Assocaites of Cleveland, Inc (01048) · Cleveland, OH
- Retina Associates of Cleveland · Cleveland, OH
Oregon · 4
- Verum Research, LLC · Eugene, OR
- EyeHealth Northwest · Portland, OR
- EyeHealth Northwest (01006) · Portland, OR
- Cascade Medical Research Institute, LLC (01070) · Springfield, OR
Pennsylvania · 2
- Eye Care Specialists · Kingston, PA
- Mid Atlantic Retina - Philadelphia (01017) · Philadelphia, PA
South Carolina · 4
- Charleston Neuroscience Institute (01037) · Beaufort, SC
- Retina Consultants of Carolina, PA (01073) · Greenville, SC
- Charleston Neuroscience Institute LLC - Ladson · Ladson, SC
- Charleston Neuroscience Institute, LLC - Mount Pleasant (01051) · Mt. Pleasant, SC
South Dakota · 1
- Ophthalmology Ltd. (01084) · Sioux Falls, SD
Tennessee · 1
- Tennessee Retina, PC (01063) · Nashville, TN
Texas · 13
- Retina Consultants of Texas - Abilene (01035) · Abilene, TX
- Austin Retina Associates · Austin, TX
- Retina Consultants of Texas - Bellaire (01067) · Bellaire, TX
- Texas Retina Associates · Dallas, TX
- Retina Consultants of Texas - Katy · Katy, TX
- Valley Retina Institute- McAllen (01076) · McAllen, TX
- Austin Retina Associates - Round Rock (01032) · Round Rock, TX
- Retina Consultants of Texas - San Antonio Medical Center · San Antonio, TX
- Austin Retina Associate (01046) · San Marcos, TX
- Retina Consultants of Texas (01055) · Schertz, TX
- Retina Center of Texas - Southlake · Southlake, TX
- Retina Consultants of Texas - The Woodlands · The Woodlands, TX
- Tyler Retina Consultants · Tyler, TX
Utah · 2
- Retina Associates of Utah (01052) · Salt Lake City, UT
- Salt Lake Retina (01044) · West Jordan, UT
Virginia · 1
- Piedmont Eye Center (01097) · Lynchburg, VA
Wisconsin · 1
- University of Wisconsin Health - University Station Clinic · Madison, WI
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.