A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis
NCT07196748
This study is recruiting at 51 US sites in 19 states, according to its ClinicalTrials.gov record last updated .
Summary
The purpose of this protocol is to evaluate the efficacy (how well it works), safety and tolerability of oral icotrokinra as therapy in adult and adolescent participants with moderately to severely active ulcerative colitis (UC, a chronic disease of the large intestine in which the lining of the colon becomes inflamed and develops tiny open ulcers).
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Colitis, Ulcerative
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 3
- Ages
- 12 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Janssen Research & Development, LLC
- Last updated on ClinicalTrials.gov
- September 25, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Arizona · 3
- AZ Gastro Care · Chandler, AZ
- Research Solutions of Arizona · Litchfield Park, AZ
- Mayo Clinic · Scottsdale, AZ
California · 10
- Clinnova Research · Anaheim, CA
- Southern California Research Center · Coronado, CA
- Om Research LLC · Lancaster, CA
- GastroIntestinal Bioscience · Los Angeles, CA
- TLC Clinical Research Inc · Los Angeles, CA
- Hoag Memorial Hospital · Newport Beach, CA
- Om Research LLC 2 · Oxnard, CA
- Stanford Medicine Children's Health · Palo Alto, CA
- Medical Associates Research Group, Inc. · San Diego, CA
- University of California San Francisco · San Francisco, CA
Colorado · 1
- Peak Gastroenterology Associates · Colorado Springs, CO
Connecticut · 1
- Connecticut Children's Medical Center · Hartford, CT
Florida · 4
- American Institute of Research · Cutler Bay, FL
- Nature Coast Clinical Research · Inverness, FL
- Florida Research Institute · Lakewood Rch, FL
- GCP Clinical Research · Tampa, FL
Georgia · 3
- Atlanta Gastroenterology Associates · Atlanta, GA
- Children's Center for Digestive Health Care · Atlanta, GA
- Gastroenterolgy Associates of Central GA · Macon, GA
Indiana · 1
- IU Health University Hospital · Indianapolis, IN
Kansas · 1
- Cotton O'Neil Digestive Health Center · Topeka, KS
Kentucky · 1
- Tri-State Gastroenterology Assoc · Crestview Hills, KY
Louisiana · 1
- Delta Research Partners, LLC · West Monroe, LA
Maryland · 2
- Chevy Chase Clinical Research · Chevy Chase, MD
- Woodholme Gastroenterology Associates · Glen Burnie, MD
New York · 6
- Westchester Putnam Gastroenterology · Carmel, NY
- Icahn School of Medicine at Mount Sinai · New York, NY
- Inflammatory Bowel Disease Center at NYU Langone · New York, NY
- Lenox Hill Hospital · New York, NY
- New York Gastroenterology Associates · New York, NY
- Weill Cornell Medical College · New York, NY
North Carolina · 2
- University of North Carolina · Chapel Hill, NC
- Atrium Health · Charlotte, NC
Oregon · 1
- The Oregon Clinic · Portland, OR
Pennsylvania · 4
- Susquehanna Research Group · Harrisburg, PA
- Penn State Milton S Hershey Medical Ctr · Hershey, PA
- Jefferson Digestive Health Institute · Philadelphia, PA
- University of Pennsylvania · Philadelphia, PA
Rhode Island · 1
- University Gastroenterology · Providence, RI
Texas · 6
- The University of Texas at Austin · Austin, TX
- DFW Clinical Trials · Carrollton, TX
- Victorium Clinical Research · Houston, TX
- Southern Star Research Institute, LLC · San Antonio, TX
- GI Alliance Southlake · Southlake, TX
- Tyler Research Institute, LLC · Tyler, TX
Virginia · 2
- Gastroenterology Associates of Tidewater · Chesapeake, VA
- Blue Ridge Medical Research · Lynchburg, VA
Washington · 1
- GI Alliance Tacoma · Tacoma, WA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.