Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)
NCT07157774
This study is recruiting at 121 US sites in 31 states, according to its ClinicalTrials.gov record last updated .
Summary
The purpose of this study is to evaluate the efficacy of muvalaplin in reducing cardiovascular risk in participants with high lipoprotein(a) who have cardiovascular disease or are at risk of a heart attack or stroke.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Elevated Lp(a)
- Atherosclerotic Cardiovascular Disease (ASCVD)
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 3
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Eli Lilly and Company
- Last updated on ClinicalTrials.gov
- September 24, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Arizona · 6
- Prime Medical Group, LLC dba Gilbert Center for Family Medicine, LLC · Gilbert, AZ
- Onyx Clinical Research · Phoenix, AZ
- Clinical Research Institute of Arizona (CRI) - Sun City West · Sun City West, AZ
- Southwest Kidney Institute - Surprise · Surprise, AZ
- Eclipse Clinical Research · Tucson, AZ
- Pima Heart · Tucson, AZ
California · 7
- National Heart Institute · Beverly Hills, CA
- John Muir Medical Center - Concord Campus · Concord, CA
- Neighborhood Healthcare Institute of Health · Escondido, CA
- Ark Clinical Research - Fountain Valley · Fountain Valley, CA
- Care Access - Huntington Beach · Huntington Beach, CA
- The Cardiovascular Center · Redding, CA
- UCLA South Bay Endocrinology · Torrance, CA
Colorado · 2
- University of Colorado Anschutz Medical Campus · Aurora, CO
- Legacy Clinical Trials · Colorado Springs, CO
Connecticut · 2
- Cardiology Associates of Fairfield County, P.C. · Stamford, CT
- Chase Medical Research, LLC · Waterbury, CT
Florida · 15
- Excel Medical Clinical Trials · Boca Raton, FL
- American Research Institute · Cutler Bay, FL
- Arrow Clinical Trials · Daytona Beach, FL
- K2 Medical Research - Daytona Beach · Daytona Beach, FL
- Soffer Health Institute · Hollywood, FL
- Jacksonville Center for Clinical Research · Jacksonville, FL
- K2 MEDICAL Research THE VILLAGES · Lady Lake, FL
- K2 Medical Research - Maitland · Maitland, FL
- K2 Medical Research ORLANDO · Maitland, FL
- Dade Florida Clinical Research Center · Miami, FL
- Onhealth Research Center · Miami, FL
- Advanced Research for Health Improvement, LLC · Naples, FL
- Renstar Medical Research · Ocala, FL
- Care Access - Tamarac · Tamarac, FL
- Care Access - Tampa · Tampa, FL
Georgia · 4
- Masters of Clinical Research · Augusta, GA
- Southeastern Clinical Research Institute · Augusta, GA
- Center for Advanced Research & Education · Gainesville, GA
- North Georgia Clinical Research · Woodstock, GA
Idaho · 3
- Elite Clinical Trials · Blackfoot, ID
- High Desert Heart & Vascular · Meridian, ID
- Elite Clinical Trials · Rexburg, ID
Illinois · 3
- Great Lakes Clinical Trials - Ravenswood · Chicago, IL
- Clinical Investigation Specialists · Gurnee, IL
- AMR Clinical · Niles, IL
Indiana · 2
- IU Health Bloomington · Bloomington, IN
- Indiana University Health Methodist Hospital · Indianapolis, IN
Louisiana · 1
- Tulane University School of Medicine · New Orleans, LA
Maine · 1
- MaineHealth Cardiology · Scarborough, ME
Maryland · 6
- Ascension Saint Agnes Heart Care · Baltimore, MD
- Metropolitan Cardiovascular Consultants · Beltsville, MD
- Flourish Research - Bowie · Bowie, MD
- Centennial Medical Group · Columbia, MD
- Johns Hopkins University · Columbia, MD
- Anderson Medical Research · Ft. Washington, MD
Massachusetts · 3
- Brigham and Women's Hospital Diabetes Program · Boston, MA
- Lucida Clinical Trials · New Bedford, MA
- Care Access - Quincy · Quincy, MA
Michigan · 2
- Revival Research Institute, LLC · Dearborn, MI
- Arcturus Healthcare , PLC, Troy Internal Medicine Research Division · Troy, MI
Montana · 1
- Boeson Research MSO · Missoula, MT
Nevada · 4
- Clinical Research of South Nevada · Las Vegas, NV
- Vector Clinical Trials · Las Vegas, NV
- Renascor Clinical Research · Reno, NV
- Vector Clinical Trials · Sparks, NV
New Jersey · 2
- Clinical Research of Philadelphia · Pennington, NJ
- Cardio Metabolic Institute · Somerset, NJ
New Mexico · 2
- IMA Clinical Research · Albuquerque, NM
- Southwest Cardiovascular Center · Albuquerque, NM
New York · 6
- Capital Cardiology Associates · Albany, NY
- NYC Research · New York, NY
- Weill Cornell Medical College · New York, NY
- Rochester Clinical Research, LLC · Rochester, NY
- SUNY Upstate Medical University · Syracuse, NY
- Southgate Medical Group · West Seneca, NY
North Carolina · 2
- Care Access - Fayetteville · Fayetteville, NC
- Medication Management · Greensboro, NC
Ohio · 1
- Velocity Clinical Research, Cincinnati, Mt. Auburn · Cincinnati, OH
Oregon · 2
- Kaiser Permanente Sunnyside Medical Center · Clackamas, OR
- Advanced Research Institute - Tigard · Portland, OR
Pennsylvania · 5
- Lehigh Valley Health Network · Allentown, PA
- Capital Area Research, LLC · Camp Hill, PA
- Altoona Center For Clinical Research · Duncansville, PA
- Clinical Research of Philadelphia · Philadelphia, PA
- Keystone Clinical Studies · Plymouth Meeting, PA
South Carolina · 2
- M3 Wake Research - Charleston · Charleston, SC
- Walker Family Care · Little River, SC
South Dakota · 1
- Circle Clinical Research · Sioux Falls, SD
Tennessee · 2
- WR-Clinsearch, LLC · Chattanooga, TN
- The Jackson Clinic · Jackson, TN
Texas · 18
- PharmaTex Research · Amarillo, TX
- St. David's Heart & Vascular PLLC dba Austin Heart · Austin, TX
- Velocity Clinical Research, Austin · Austin, TX
- Dallas VA Medical Center · Dallas, TX
- IntraCare · Dallas, TX
- Renal Disease Research Institute · Dallas, TX
- Southwest Family Medicine Associates · Dallas, TX
- UT Southwestern Medical Center · Dallas, TX
- Cedar Health Research - Fort Worth · Fort Worth, TX
- Texas Health Research & Education Institute - Fort Worth · Fort Worth, TX
- Center for Cardiometabolic Disease Prevention/Baylor College of Medicine · Houston, TX
- Research Physicians Network, LLC · Houston, TX
- GMG Clinical Research (DBA Radiance Clinical Research) - Lampasas · Lampasas, TX
- Biopharma Informatic, LLC · McAllen, TX
- Revival Research Institute, LLC · McKinney, TX
- PRX Research · Mesquite, TX
- ERA Health Research-Texas · Midland, TX
- Sherman Clinical Research · Sherman, TX
Utah · 3
- Intermountain Medical Center · Murray, UT
- Advanced Research Institute · Ogden, UT
- Ogden Clinic - Canyon View · Ogden, UT
Virginia · 7
- Virginia Heart · Falls Church, VA
- Carient Heart & Vascular - Manassas · Manassas, VA
- Manassas Clinical Research Center · Manassas, VA
- TPMG (Tidewater Physicians Multispecialty Group) Clinical Research · Newport News, VA
- York Clinical Research · Norfolk, VA
- Dominion Medical Associates, Inc. · Richmond, VA
- Carilion Clinic · Roanoke, VA
Washington · 5
- ERA Health Research - CardioNow - Lynnwood · Lynnwood, WA
- Eastside Research Associates · Redmond, WA
- Rainier Clinical Research Center · Renton, WA
- Universal Research Group · Tacoma, WA
- Central Washington Health Services Association d/b/a Confluence Health · Wenatchee, WA
Wisconsin · 1
- Clinical Investigation Specialists · Kenosha, WI
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.