A Study to Assess Adverse Events and Change in Disease Activity of Intravenous (IV) Telisotuzumab Adizutecan, Monotherapy or in Combination With Osimertinib, Compared to Standard of Care in Adult Participants With Locally Advanced or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer
NCT07155187
This study is recruiting at 16 US sites in 10 states, according to its ClinicalTrials.gov record last updated .
Summary
Non-small cell lung cancer (NSCLC) is a common type of lung cancer where abnormal cells in the lungs grow out of control. The purpose of this study is to assess adverse events and change in disease activity of telisotuzumab adizutecan as a monotherapy or in combination with osimertinib compared to standard of care (SOC). Telisotuzumab adizutecan is an investigational drug being developed for the treatment of NSCLC.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Non-Small Cell Lung Cancer
- c-MET
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 2/3
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- AbbVie
- Last updated on ClinicalTrials.gov
- October 5, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Arkansas · 1
- Highlands Oncology Group - Springdale /ID# 277132 · Springdale, AR
California · 3
- City of Hope National Medical Center /ID# 277005 · Duarte, CA
- City of Hope - Orange County Lennar Foundation Cancer Center /ID# 277928 · Irvine, CA
- UC San Diego Health - Moores Cancer Center /ID# 278836 · La Jolla, CA
Florida · 3
- Cancer Specialists of North Florida /ID# 277332 · Jacksonville, FL
- Cancer Care Centers of Brevard- Rockledge /ID# 277853 · Rockledge, FL
- Moffitt Cancer Center /ID# 276785 · Tampa, FL
Indiana · 1
- Parkview Research Center /ID# 277651 · Fort Wayne, IN
Minnesota · 1
- HealthPartners Cancer Research Center /ID# 277339 · Saint Louis Park, MN
Nebraska · 1
- Nho - Revive Research Institute /ID# 277569 · Lincoln, NE
New Hampshire · 1
- Dartmouth-Hitchcock Medical Center /ID# 277673 · Lebanon, NH
New Jersey · 1
- Astera Cancer Care /ID# 277570 · East Brunswick, NJ
Tennessee · 2
- Tennessee Cancer Specialists - Knoxville - Old Weisgarber Road /ID# 277891 · Knoxville, TN
- SCRI Oncology Partners /ID# 276959 · Nashville, TN
Washington · 2
- Fred Hutchinson Cancer Center. /ID# 277939 · Seattle, WA
- Northwest Cancer Specialists - Vancouver /ID# 277855 · Vancouver, WA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.