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A Study to Compare Different Doses of Tifeglipron (RO7795081) With Placebo or Semaglutide in People With Type 2 Diabetes

NCT07112872

This study is recruiting at 10 US sites in 7 states, according to its ClinicalTrials.gov record last updated .

Summary

This multicenter, randomized, double-blind, placebo- and open-label active comparator-controlled, parallel-group, dose-range-finding, Phase II study aims to evaluate the efficacy, tolerability, and safety of different doses of tifeglipron for glycemic control in adult participants with Type 2 diabetes mellitus (T2D).

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Type 2 Diabetes Mellitus

Eligibility basics and study details

Study type
Interventional
Phase
Phase 2
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
Hoffmann-La Roche
Last updated on ClinicalTrials.gov
November 12, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Arizona · 1

  • Arizona Liver Health - Tucson · Tucson, AZ

California · 3

  • Orange County Research Center · Lake Forest, CA
  • Prospective Research Innovations Inc. · Rancho Cucamonga, CA
  • Encompass Clinical Research · Spring Valley, CA

Connecticut · 1

  • Chase Medical Research · Waterbury, CT

District of Columbia · 1

  • Emerson Clinical Research Institute · Washington D.C., DC

North Carolina · 2

  • Accellacare of Piedmont Healthcare · Statesville, NC
  • Accellacare of Wilmington, LLC · Wilmington, NC

Pennsylvania · 1

  • Tristar Clinical Investigations · Philadelphia, PA

Virginia · 1

  • Manassas Clinical Research Center · Manassas, VA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.