A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations
NCT07109726
This study is recruiting at 15 US sites in 13 states, according to its ClinicalTrials.gov record last updated .
Summary
This is a Phase 1/2, open-label, multicenter study evaluating the safety, tolerability, pharmacokinetics, pharmacodynamics and anti-tumor activity of TER-2013 in patients with advanced solid tumors harboring AKT/PI3K/PTEN pathway alterations.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Breast Cancer
- Endometrial Cancer
- Ovarian Cancer
- Lung Squamous Cell Carcinoma
- Head and Neck Squamous Cell Carcinoma
- Esophageal Squamous Cell Carcinoma
- Solid Tumor
- Cervical Cancer
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 1/2
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Terremoto Biosciences Inc.
- Last updated on ClinicalTrials.gov
- September 17, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
California · 2
- City of Hope · Duarte, CA
- City of Hope, Irvine · Irvine, CA
Florida · 1
- Florida Cancer Specialists - Lake Nona · Orlando, FL
Illinois · 1
- City of Hope, Chicago · Zion, IL
Massachusetts · 1
- Massachusetts General Hospital · Boston, MA
Minnesota · 1
- Mayo Rochester · Rochester, MN
Missouri · 1
- Washington Univ. School of Medicine · St Louis, MO
Nebraska · 1
- Nebraska Cancer Specialists · Omaha, NE
Ohio · 1
- UH Cleveland Medical Center · Cleveland, OH
Tennessee · 1
- Sarah Cannon Nashville · Nashville, TN
Texas · 2
- MD Anderson Cancer Center · Houston, TX
- START Center for Cancer Research · San Antonio, TX
Utah · 1
- START Center for Cancer Research · West Valley City, UT
Virginia · 1
- NEXT Oncology · Fairfax, VA
Wisconsin · 1
- Froedtert & MCW Cancer Center · Milwaukee, WI
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.