A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer
NCT07102381
This study is recruiting at 29 US sites in 18 states, according to its ClinicalTrials.gov record last updated .
Summary
The purpose of this study is to see if zanidatamab is safe and effective, when combined with chemotherapy, in treating people who has Human Epidermal Growth Factor Receptor 2 (HER2)-positive, early-stage breast cancer
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- HER2-positive Breast Cancer
- Breast Cancer
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 2
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Jazz Pharmaceuticals
- Last updated on ClinicalTrials.gov
- October 1, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
California · 2
- Oncology Institute · Long Beach, CA
- Cancer & Blood Research Center · Los Alamitos, CA
Colorado · 1
- Rocky Mountain Cancer Centers · Denver, CO
Florida · 2
- Holy Cross Hospital · Fort Lauderdale, FL
- The Oncology Institute · Lakeland, FL
Iowa · 1
- Accellacare of McFarland · Ames, IA
Louisiana · 1
- LSU Health Sciences Center · Shreveport, LA
Maine · 1
- New England Cancer Specialists · Scarborough, ME
Maryland · 1
- Maryland Oncology Hematology · Laurel, MD
Michigan · 1
- Henry Ford Hospital · Detroit, MI
Nebraska · 2
- Cancer Partners of Nebraska · Lincoln, NE
- Nebraska Cancer Specialists · Omaha, NE
New Jersey · 2
- Astera Cancer Care (Formerly Regional Cancer Care Associates) · East Brunswick, NJ
- Medical Oncology Hematology Associates · Newark, NJ
New Mexico · 1
- The University of New Mexico · Albuquerque, NM
New York · 2
- Hematology Oncology Associates of Central New York · Camillus, NY
- Memorial Sloan Kettering Cancer Center · New York, NY
North Carolina · 1
- Levine Cancer · Charlotte, NC
Tennessee · 1
- Sarah Cannon Research Institute (Nashville) · Nashville, TN
Texas · 4
- Texas Oncology DFW · Dallas, TX
- The University of Texas Southwestern Medical Center · Dallas, TX
- Texas Oncology Gulf Coast · Houston, TX
- UT Health San Antonio, Mays Cancer Center · San Antonio, TX
Virginia · 3
- Virginia Cancer Specialists · Fairfax, VA
- Virginia Oncology Associates · Norfolk, VA
- Shenandoah Oncology · Winchester, VA
Washington · 2
- Northwest Medical Specialties · Puyallup, WA
- Northwest Cancer Specialists · Vancouver, WA
Wisconsin · 1
- University of Wisconsin · Madison, WI
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.