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Propranolol for Aggression, Self-Injury, and Severe Disruptive Behavior in Adolescents and Adults With Autism

NCT07091279

This study is recruiting at 2 US sites in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

The goal of this clinical trial is to learn if propranolol can help reduce challenging behaviors associated with Autism Spectrum Disorder, including aggression, self-injury, and severe disruptive behaviors. Participants will be randomly assigned to receive either propranolol or a placebo (a look-alike substance that contains no drug) daily for 12 weeks. After the 12 weeks, all participants will have the opportunity to receive propranolol for an additional 12 weeks.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Autism Spectrum Disorder
  • Challenging Behaviour
  • Aggression
  • Severe Disruptive Behaviour Disorders
  • Self-injury

Eligibility basics and study details

Study type
Interventional
Phase
Phase 2
Ages
12 to 40 years
Sex
All
Healthy volunteers
Not accepted
Sponsor
Jeremy Veenstra-vanderweele
Last updated on ClinicalTrials.gov
September 1, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

New York · 2

  • New York State Institute for Basic Research (IBR) · Staten Island, NY
  • Center for Autism and the Developing Brain · White Plains, NY

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.