Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)
NCT07007065
This study is recruiting at 54 US sites in 21 states, according to its ClinicalTrials.gov record last updated .
Summary
Neovascular age-related macular degeneration (nAMD), also known as "wet" AMD, is the abnormal growth of new blood vessels in the light-sensitive tissue at the back of the eye called the retina. The purpose of this study is to assess how safe and effective Surabgene Lomparvovec is in treating participants with Neovascular age-related macular degeneration (nAMD). Surabgene Lomparvovec (ABBV-RGX-314) is an investigational gene therapy being developed for the treatment of neovascular age-related macular degeneration (nAMD). Participants will be placed into 1 of 3 groups, called treatment arms.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Neovascular Age-related Macular Degeneration
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 3
- Ages
- 50 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- AbbVie
- Last updated on ClinicalTrials.gov
- October 8, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Arizona · 2
- Barnet Dulaney Perkins Eye Center - Mesa /ID# 279265 · Mesa, AZ
- American Vision Partners /ID# 264615 · Sun City, AZ
California · 12
- Retinal Diagnostic Center /ID# 263054 · Campbell, CA
- The Retina Partners /ID# 263265 · Encino, CA
- Retina Associates of Southern California /ID# 263056 · Huntington Beach, CA
- Shiley Eye Institute At Uc San Diego Health /ID# 276682 · La Jolla, CA
- Northern California Retina Vitreous Associates - Mountain View /ID# 263990 · Mountain View, CA
- Eye Research Foundation /ID# 277345 · Newport Beach, CA
- Retina Consultants of San Diego /ID# 264026 · Poway, CA
- Retina Consultants Of Southern California - Redlands /ID# 276496 · Redlands, CA
- Kaiser Permanente - Riverside Medical Center /ID# 263253 · Riverside, CA
- Retinal Consultants - Sacramento - Greenback Lane /ID# 263983 · Sacramento, CA
- UCSF, Wayne and Gladys Valley Center for Vision /ID# 263058 · San Francisco, CA
- Orange County Retina Medical Group /ID# 266612 · Santa Ana, CA
Colorado · 3
- Retina Consultants of Southern Colorado /ID# 263284 · Colorado Springs, CO
- Colorado Retina Associates /ID# 263247 · Lakewood, CO
- Advanced Vision Surgery Center /ID# 264208 · Longmont, CO
Florida · 5
- Advanced Research, LLC /ID# 276526 · Deerfield Beach, FL
- Segal Drug Trials, Inc /ID# 276966 · Delray Beach, FL
- Retina Vitreous Consultants LLP business DBA as Retina Group of Florida /ID# 264631 · Fort Myers, FL
- Florida Retina Institute - Orlando /ID# 263288 · Orlando, FL
- Center for Retina and Macular Disease /ID# 264201 · Winter Haven, FL
Georgia · 1
- Southeast Retina Center /ID# 263264 · Augusta, GA
Illinois · 2
- Vision Medical Research /ID# 277102 · Oak Lawn, IL
- Springfield Clinic Main Campus /ID# 265202 · Springfield, IL
Indiana · 1
- Midwest Eye Institute North Indianapolis /ID# 264031 · Carmel, IN
Iowa · 1
- Wolfe Eye Clinic - West Des Moines /ID# 263270 · West Des Moines, IA
Kansas · 1
- Retina Associates - Lenexa /ID# 264607 · Lenexa, KS
Maine · 1
- Maine Eye Center - Marginal Way Campus /ID# 263251 · Portland, ME
Maryland · 2
- The Retina Care Center /ID# 263263 · Baltimore, MD
- Retina Specialist /ID# 264633 · Towson, MD
Michigan · 1
- Associated Retinal Consultants /ID# 263289 · Royal Oak, MI
Minnesota · 2
- Retina Consultants of Minnesota (RCM) - Edina Retina Clinic /ID# 279427 · Edina, MN
- Mayo Clinic - Minnesota /ID# 263977 · Rochester, MN
Missouri · 1
- Retina Institute - St. Louis /ID# 263985 · St Louis, MO
Nevada · 1
- Sierra Eye Associates /ID# 263240 · Reno, NV
New Jersey · 1
- Monmouth Retina Consultants /ID# 279252 · Little Silver, NJ
Ohio · 3
- Cleveland Clinic - Cleveland /ID# 264210 · Cleveland, OH
- Ohio State Havener Eye Institute - Columbus /ID# 263987 · Columbus, OH
- Midwest Retina /ID# 263231 · Dublin, OH
Pennsylvania · 2
- Erie Retina Research /ID# 263287 · Erie, PA
- Mid Atlantic Retina - Philadelphia /ID# 263291 · Philadelphia, PA
South Carolina · 4
- Charleston Neuroscience Institute - Bluffton /ID# 264037 · Bluffton, SC
- Charleston Neuroscience Institute - Charleston /ID# 276425 · Charleston, SC
- Retina Consultants of South Carolina - Ladson /ID# 277596 · Ladson, SC
- Retina Consultants of America /ID# 264038 · Mt. Pleasant, SC
Texas · 7
- Retina Research Institute of Texas /ID# 263233 · Abilene, TX
- Austin Clinical Research, LLC /ID# 263229 · Austin, TX
- Austin Retina Associates - Austin /ID# 266770 · Austin, TX
- Star Retina /ID# 266386 · Burleson, TX
- Retina Consultants of Texas /ID# 263274 · Houston, TX
- Austin Retina Associates - Round Rock /ID# 266776 · Round Rock, TX
- Retina Consultants of Texas - Westover /ID# 264209 · San Antonio, TX
Utah · 1
- Rocky Mountain Retina Consultants /ID# 263266 · Murray, UT
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.