Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer
NCT06995677
This study is recruiting at 36 US sites in 17 states, according to its ClinicalTrials.gov record last updated .
Summary
Phase 2 Study of TYRA-300 in FGFR3 Altered Low Grade, Intermediate Risk NMIBC
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Low-grade NMIBC
- FGFR Gene Amplification
- FGFR Gene Alterations
- FGFR3 Gene Alteration
- FGFR3 Gene Mutation
- FGFR3 Gene Fusions
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 2
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Tyra Biosciences, Inc
- Last updated on ClinicalTrials.gov
- September 29, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alabama · 1
- Urology Centers of Alabama · Homewood, AL
Arkansas · 1
- Arkansas Urology · Little Rock, AR
California · 3
- Tri Valley Urology - Murrieta · Murrieta, CA
- Eisenhower Medical Associates · Rancho Mirage, CA
- Om Research LLC · San Diego, CA
Illinois · 2
- Associated Urological Specialists · Chicago Ridge, IL
- Duly Health and Care · Lisle, IL
Indiana · 2
- Urology of Indiana · Greenwood, IN
- First Urology · Jeffersonville, IN
Kansas · 1
- University of Kansas Medical Center (KUMC) · Kansas City, KS
Maryland · 1
- Johns Hopkins University · Baltimore, MD
Massachusetts · 1
- Greater Boston Urology · Plymouth, MA
Missouri · 1
- Specialty Clinical Research of St. Louis · St Louis, MO
New Jersey · 2
- Atlantic Health System · Morristown, NJ
- New Jersey Urology, LLC (Summit Health - Washington Township) · Voorhees Township, NJ
New York · 6
- Icahn School of Medicine at Mount Sinai (ISMMS) - Mount Sinai Queens - Infusion Center · Astoria, NY
- Memorial Sloan Kettering Cancer Center - Sidney Kimmel Center for Prostate and Urologic Cancers · New York, NY
- NYU Langone Health · New York, NY
- Associated Medical Professionals of NY · Syracuse, NY
- State University of New York (SUNY) Upstate Medical University · Syracuse, NY
- The Bronx Veterans Medical Research Foundation, Inc. · The Bronx, NY
North Carolina · 2
- Duke Cancer Institute · Durham, NC
- Associate Urologist of North Carolina · Raleigh, NC
Ohio · 2
- The James at Brain and Spine Hospital (OSU) · Columbus, OH
- Oregon Urology Institute · Springfield, OH
Pennsylvania · 2
- MidLantic Urology · Bala-Cynwyd, PA
- Keystone Urology Specialists · Lancaster, PA
South Carolina · 3
- Medical University of South Carolina · Charleston, SC
- Carolina Urologic Research Center · Myrtle Beach, SC
- Lowcounty Urology Clinics, P.A. · North Charleston, SC
Tennessee · 2
- Conrad Pearson-Memphis · Germantown, TN
- Urology Associates PC · Nashville, TN
Texas · 4
- Urology Austin · Austin, TX
- Urology Clinics of North Texas · Dallas, TX
- Baylor College of Medicine · Houston, TX
- Urology San Antonio · San Antonio, TX
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.