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Ultra-hypofractionated Whole Breast Irradiation With Lumpectomy Cavity Boost for the Treatment of Stage I-III Breast Cancer

NCT06954831

This study is recruiting at 6 US sites in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

This clinical trial tests how well ultra-hypofractionated (UF) whole breast irradiation (WBI) with lumpectomy cavity boost (CB) works in treating patients with stage I-III breast cancer. Breast conservation therapy (BCT) is the recommended treatment for patients with early stage breast cancer. BCT involves a lumpectomy followed by breast radiation. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill tumor cells and shrink tumors.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Anatomic Stage I Breast Cancer AJCC v8
  • Anatomic Stage II Breast Cancer AJCC v8
  • Anatomic Stage III Breast Cancer AJCC v8
  • Breast Carcinoma

Eligibility basics and study details

Study type
Interventional
Phase
Phase 2
Ages
40 years and older
Sex
Female
Healthy volunteers
Not accepted
Sponsor
City of Hope Medical Center
Last updated on ClinicalTrials.gov
October 29, 2025

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

California · 6

  • City of Hope at Arcadia · Arcadia, CA
  • City of Hope Medical Center · Duarte, CA
  • City of Hope Antelope Valley · Lancaster, CA
  • City of Hope South Pasadena · South Pasadena, CA
  • City of Hope at South Bay · Torrance, CA
  • City of Hope Upland · Upland, CA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.