A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression
NCT06906939
This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .
Summary
Osteoarthritis (OA) is a major public health problem, and involvement of the knee is especially disabling. Symptomatic knee OA has an incidence rate between 40 to 1,020 per 100,000 person years1 and is among the most common causes of disability worldwide. Knee arthritis pain and disability are highly comorbid wiht depression (30-50%). Currently available treatments offer only limited relief. The Pilot project aims to establish feasibility of the rTMS neuromodulation of response to Tai Chi and improvement in pain and comorbid depression in patients with knee OA.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Knee Osteoarthritis
- Depression
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Early Phase 1
- Ages
- 50 to 95 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- University of California, Los Angeles
- Last updated on ClinicalTrials.gov
- July 6, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
California · 1
- UCLA Semel Institute - Neuropsychiatric Institute (NPI) · Los Angeles, CA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.