Ovarian-Sparing Adaptive Radiotherapy in Young Adult Women
NCT06904365
This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .
Summary
Female patients with early onset (<50 years old) pelvic malignancies such as uterine and rectal cancers are rising in incidence, which often requires pelvic radiation; many of these patients are premenopausal and at a high risk of premature ovarian failure from radiotherapy. Premature ovarian failure carries significant cardiac, musculoskeletal, sexual, and psychosocial morbidity. Ovarian transposition carries variable success rates, is not readily accessible to the general population, and can still be at risk of clinically significant radiotherapy doses.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Uterine Cancer
- Rectal Cancer
- Colon Cancer
- Breast Cancer
- Lung Cancer
- Sarcoma
- Cervix Cancer
- Head and Neck Cancer
- Anal Cancer
- Liver Cancer
- Gastric Cancer
- Bladder Cancer
Eligibility basics and study details
- Study type
- Observational
- Phase
- Not applicable
- Ages
- 18 to 50 years
- Sex
- Female
- Healthy volunteers
- Not accepted
- Sponsor
- Washington University School of Medicine
- Last updated on ClinicalTrials.gov
- September 2, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Missouri · 1
- Washington University School of Medicine · St Louis, MO
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.