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Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients

NCT06903819

This study is recruiting at 2 US sites in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

The goal of this clinical trial is to learn if ketamine, given during surgery, can help improve recovery for adults with serious orthopedic trauma. The study will test whether ketamine reduces pain, lowers the need for opioids, and improves mental health outcomes like depression and post-traumatic stress disorder (PTSD). The main questions it aims to answer are: Does ketamine reduce pain after surgery compared to standard anesthesia? Does ketamine reduce the amount of opioids patients need for pain control? Does ketamine improve symptoms of depression and PTSD after orthopedic trauma?

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Orthopedic Trauma Surgery Patients
  • Postoperative Pain
  • Opioid Use
  • Depression
  • Post-traumatic Stress Disorder (PTSD)

Eligibility basics and study details

Study type
Interventional
Phase
Phase 4
Ages
18 to 65 years
Sex
All
Healthy volunteers
Not accepted
Sponsor
Texas Tech University Health Sciences Center
Last updated on ClinicalTrials.gov
March 24, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Texas · 2

  • Texas Tech University Health Sciences Center Lubbock · Lubbock, TX
  • University Medical Center · Lubbock, TX

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.