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A Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE

NCT06897930

This study is recruiting at 10 US sites in 7 states, according to its ClinicalTrials.gov record last updated .

Summary

This is a Phase 1b/2, single-arm, open-label, multi-center, clinical study of AZD0120, a CD19/BCMA dual CAR T cell therapy, to evaluate the safety, tolerability, and efficacy in adult participants with refractory Systemic Lupus Erythematosus.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Lupus Erythematosus, Systemic

Eligibility basics and study details

Study type
Interventional
Phase
Phase 1/2
Ages
18 to 70 years
Sex
All
Healthy volunteers
Not accepted
Sponsor
AstraZeneca
Last updated on ClinicalTrials.gov
September 10, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

California · 1

  • Research Site · San Francisco, CA

Georgia · 1

  • Research Site · Atlanta, GA

Massachusetts · 1

  • Research Site · Boston, MA

Missouri · 1

  • Research Site · St Louis, MO

New York · 2

  • Research Site · New York, NY
  • Research Site · Syracuse, NY

North Carolina · 2

  • Research Site · Chapel Hill, NC
  • Research Site · Charlotte, NC

Washington · 2

  • Research Site · Seattle, WA
  • Research Site · Seattle, WA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.