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A Mechanistic Study to Assess a Single Dose of CYB003 in Participants With Depression and Anxiety

NCT06820723

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

The goal of this study is to learn how psychedelics may help symptoms of depression and anxiety. Participants with major depressive disorder experiencing symptoms of depression and anxiety will receive one dose of either a drug related to psilocybin or a placebo. Assessments include interviews, self-report questionnaires, EEG and fMRI to measure symptoms and brain function.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Depression
  • Anxiety
  • Major Depressive Disorder

Eligibility basics and study details

Study type
Interventional
Phase
Phase 2
Ages
21 to 65 years
Sex
All
Healthy volunteers
Not accepted
Sponsor
Ohio State University
Last updated on ClinicalTrials.gov
July 23, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Ohio · 1

  • The Ohio State University Department of Psychiatry · Columbus, OH

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.