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A Study Evaluating Neoadjuvant Chemoimmunotherapy With Immunosensitizing Radiation for Borderline Resectable Non-Small Cell Lung Cancer

NCT06800339

This study is recruiting at 4 US sites in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

The purpose of this research study is to find out if adding radiation prior to chemoimmunotherapy and surgery is effective for people with non-small cell lung cancer (NSCLC) who have the potential for surgery. Standard of Care Chemoimmunotherapy: For this study, standard of care chemotherapy will be used. This means this is the type of chemotherapy that is normal for your cancer. In addition to the chemotherapy, you will also receive the immunotherapy drug, nivolumab. This will be administered intravenously once every 3 weeks for up to 3 cycles (i.e.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Non-Small Cell Lung Cancer

Eligibility basics and study details

Study type
Interventional
Phase
Phase 1
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
University of Maryland, Baltimore
Last updated on ClinicalTrials.gov
May 6, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Maryland · 4

  • Maryland Proton Treatment Center · Baltimore, MD
  • University of Maryland Greenebaum Cancer Center · Baltimore, MD
  • Upper Chesapeake- Kaufman Cancer Center · Bel Air, MD
  • Baltimore Washington Medical Center- Tate Cancer Center · Glen Burnie, MD

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.