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Randomised Clinical Trial to Investigate Efficacy and Safety of Benralizumab 30 mg SC as an add-on Therapy in Uncontrolled Eosinophilic Asthma Patients Treated With Medium-dose ICS-LABA Compared to Conventional Escalation to High-dose ICS-LABA Treatment

NCT06750289

This study is recruiting at 23 US sites in 12 states, according to its ClinicalTrials.gov record last updated .

Summary

This study evaluates the efficacy and safety of benralizumab as an add-on therapy in uncontrolled eosinophilic asthma participants treated with medium-dose ICS-LABA compared to the conventional treatment step of escalation of inhaled therapy to high-dose ICS-LABA.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Eosinophilic Asthma

Eligibility basics and study details

Study type
Interventional
Phase
Phase 3
Ages
12 to 75 years
Sex
All
Healthy volunteers
Not accepted
Sponsor
AstraZeneca
Last updated on ClinicalTrials.gov
May 13, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Arizona · 2

  • Research Site · Sun City, AZ
  • Research Site · Tucson, AZ

California · 3

  • Research Site · Inglewood, CA
  • Research Site · Newport Beach, CA
  • Research Site · Pasadena, CA

Florida · 7

  • Research Site · Cape Coral, FL
  • Research Site · Lauderdale Lakes, FL
  • Research Site · Leesburg, FL
  • Research Site · Miami, FL
  • Research Site · Orlando, FL
  • Research Site · Tampa, FL
  • Research Site · Winter Park, FL

Michigan · 1

  • Research Site · Ann Arbor, MI

Nevada · 1

  • Research Site · Henderson, NV

New Jersey · 1

  • Research Site · Northfield, NJ

New York · 2

  • Research Site · New Hyde Park, NY
  • Research Site · The Bronx, NY

Oklahoma · 1

  • Research Site · Oklahoma City, OK

Pennsylvania · 1

  • Research Site · DuBois, PA

Rhode Island · 1

  • Research Site · Warwick, RI

South Carolina · 1

  • Research Site · Greenville, SC

Texas · 2

  • Research Site · McKinney, TX
  • Research Site · San Antonio, TX

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.