QuantifyHER: Quantitative Immunofluorescence and/or RT-qPCR for Measuring HER2 in HER2-low Metastatic Breast Cancer
NCT06551116
This study is recruiting at 37 US sites in 13 states, according to its ClinicalTrials.gov record last updated .
Summary
This study will assess whether a quantitative, HER2 assay can accurately and reliably discriminate between responders and non-responders among patients with HER2 IHCI+ metastatic breast cancer who are receiving T-Dxd.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- HER2-positive Metastatic Breast Cancer
Eligibility basics and study details
- Study type
- Observational
- Phase
- Not applicable
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Abramson Cancer Center at Penn Medicine
- Last updated on ClinicalTrials.gov
- July 8, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
California · 1
- University of California San Francisco Medical Center · San Francisco, CA
Connecticut · 13
- Smilow Cancer Hospital-Derby Care Center · Derby, CT
- Smilow Cancer Hospital Care Center · Fairfield, CT
- Smilow Cancer Hospital at Glastonbury · Glastonbury, CT
- Smilow Cancer Hospital Care Center at Greenwich · Greenwich, CT
- Smilow Cancer Hospital Care Center · Guilford, CT
- Smilow Cancer Hospital at Saint Francis · Hartford, CT
- Yale Cancer Center · New Haven, CT
- Yale-New Haven Hospital North Haven Medical Center · New Haven, CT
- Smilow Cancer Hospital Care Center at Long Ridge · Stamford, CT
- Smilow Cancer Hospital-Torrington Care Center · Torrington, CT
- Smilow Cancer Hospital Care Center · Trumbull, CT
- Smilow Cancer Hospital-Waterbury Care Center · Waterbury, CT
- Smilow Cancer Hospital Care Center - Waterford · Waterford, CT
District of Columbia · 3
- Georgetown University - Lombardi CCC · Washington D.C., DC
- MedStar Washington Hospital Center · Washington D.C., DC
- Sibley Memorial Hospital · Washington D.C., DC
Illinois · 3
- University of Chicago Medical Center · Chicago, IL
- University of Chicago Comprehensive Cancer Center at Silver Cross · New Lenox, IL
- University of Chicago Medicine-Orland Park · Orland Park, IL
Indiana · 1
- University of Chicago Medicine Northwest Indiana · Crown Point, IN
Maryland · 1
- John's Hopkins Hospital · Baltimore, MD
New Jersey · 1
- Penn Medicine Princeton Medical Center · Plainsboro, NJ
New York · 1
- Montefiore Einstein Medical Center · The Bronx, NY
North Carolina · 1
- UNC Chapel Hill · Chapel Hill, NC
Pennsylvania · 3
- Abramson Cancer Center of the University of Pennsylvania · Philadelphia, PA
- University of Pittsburgh Medical Center · Pittsburgh, PA
- UPMC Hillman CC · Pittsburgh, PA
Rhode Island · 1
- Smilow Cancer Hospital Care Center · Westerly, RI
Texas · 7
- Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center · Houston, TX
- Ben Taub General Hospital · Houston, TX
- MD Anderson Cancer center · Houston, TX
- MD Anderson Cancer Center · Houston, TX
- MD Anderson Cancer center · League City, TX
- MD Anderson Cancer Center · Sugar Land, TX
- MD Anderson Cancer center · Woodland, TX
Washington · 1
- University of Washington - Fred Hutchinson Cancer Center · Seattle, WA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.