Efgartigimod for the Treatment of Acute Optic Neuritis
NCT06453694
This study is recruiting at 2 US sites in 1 state, according to its ClinicalTrials.gov record last updated .
Summary
The goal of this pilot clinical trial is to test efgartigimod alfa against placebo in adults with first-time optic neuritis (optic nerve inflammation). The main questions it aims to answer are: Is it feasible to use efgartigimod alfa for optic neuritis? Is it feasible to run a larger trial testing efgartigimod alfa in optic neuritis? Does efgartigimod alfa work better than placebo in improving how quickly and how much vision returns?
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Optic Neuritis
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 2
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Anastasia Vishnevetsky, MD, MPH
- Last updated on ClinicalTrials.gov
- November 10, 2025
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Massachusetts · 2
- Massachusetts Eye and Ear Infirmary · Boston, MA
- Massachusetts General Hospital · Boston, MA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.