FiH Study to Investigate Safety, PK and Efficacy of the NaPi2b ADC TUB-040 in Patients With PROC or r/r Adenocarcinoma NSCLC
NCT06303505
This study is recruiting at 13 US sites in 11 states, according to its ClinicalTrials.gov record last updated .
Summary
The goal of this clinical study is to learn more about the study drug, TUB-040, including its safety, tolerability, pharmacokinetics, and preliminary efficacy, and to determine the best dose of TUB-040 in participants with ovarian cancer or non-small cell lung cancer (NSCLC). The primary objectives of this study are: Phase 1: To determine the safety and tolerability of TUB-040 and determine the maximum tolerated dose (MTD) or the identified dose for optimization (IDO).
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Ovarian Cancer
- Non-small Cell Lung Cancer
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 1/2
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Gilead Sciences
- Last updated on ClinicalTrials.gov
- November 3, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alabama · 1
- University of Alabama at Birmingham · Birmingham, AL
Georgia · 1
- Winship Cancer Institute Emory University · Atlanta, GA
Massachusetts · 1
- Dana Farber Cancer Institute (DFCI) · Boston, MA
New Jersey · 1
- START New Jersey (Astera Cancer Center) · East Brunswick, NJ
New York · 1
- Mount Sinai · New York, NY
Ohio · 2
- The Christ Hospital Physicians - Mt. Auburn · Cincinnati, OH
- Ohio State University CRS · Columbus, OH
Oklahoma · 1
- Stephenson Cancer Center · Oklahoma City, OK
Oregon · 1
- Asante Rogue Region al Medical Center · Medford, OR
Texas · 2
- START Dallas Fort Worth · Fort Worth, TX
- NEXT Oncology Dallas · Irving, TX
Utah · 1
- START Mountain Region · West Valley City, UT
Virginia · 1
- NEXT Virginia · Fairfax, VA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.