Exercise Facilitation of Adolescent Fear Extinction, Frontolimbic Circuitry, and Endocannabinoids
NCT06297278
This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .
Summary
Anxiety disorders commonly begin during adolescence, and are characterized by deficits in the ability to inhibit or extinguish pathological fear. Recent research has provided new understanding of how fear is learned and can be regulated in the adolescent brain, and how the endocannabinoid system shapes these processes; however, these advances have not yet translated into improved therapeutic outcomes for adolescents with anxiety. This study will test whether a behavioral intervention, acute exercise, can help to improve fear regulation by enhancing brain activity and endocannabinoid signaling.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Adolescence
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Not applicable
- Ages
- 14 to 17 years
- Sex
- All
- Healthy volunteers
- Accepted
- Sponsor
- Wayne State University
- Last updated on ClinicalTrials.gov
- August 7, 2025
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Michigan · 1
- Tolan Park Medical Building · Detroit, MI
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.