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Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset Diabetes

NCT06246799

This study is recruiting at 2 US sites in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

The primary purpose of this study is to evaluate the efficacy, durability, and mechanism of HbA1c reduction produced by the combination of pioglitazone plus tirzepatide compared to metformin plus sitagliptin in patients with recently diagnosed type 2 diabetes mellitus.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Type 2 Diabetes (Adult Onset)

Eligibility basics and study details

Study type
Interventional
Phase
Phase 3
Ages
18 to 75 years
Sex
All
Healthy volunteers
Not accepted
Sponsor
The University of Texas Health Science Center at San Antonio
Last updated on ClinicalTrials.gov
March 10, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Texas · 2

  • University Health System Texas Diabetic Institute · San Antonio, TX
  • UT Health Science Center · San Antonio, TX

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.