CtDNA Based MRD Testing for NAC Monitoring in TNBC
NCT06230185
This study is recruiting at 14 US sites in 13 states, according to its ClinicalTrials.gov record last updated .
Summary
A prospective, multicenter, observational study to evaluate the correlation of Molecular Residual Disease (MRD) detection using circulating tumor DNA guided test to pathological complete response (pCR) after neoadjuvant chemotherapy (NAC) in stage I-III triple negative breast cancer (TNBC). Results from this study aim to improve MRD detection and disease outcomes for future patients.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- TNBC - Triple-Negative Breast Cancer
- Minimal Residual Disease
Eligibility basics and study details
- Study type
- Observational
- Phase
- Not applicable
- Ages
- 18 years and older
- Sex
- Female
- Healthy volunteers
- Not accepted
- Sponsor
- Personalis Inc.
- Last updated on ClinicalTrials.gov
- January 7, 2025
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Arizona · 1
- Arizona Oncology · Tucson, AZ
Colorado · 1
- University of Colorado Cancer Center · Aurora, CO
District of Columbia · 1
- George Washington University · Washington D.C., DC
Florida · 2
- Mount Sinai Medical Center of Florida · Miami Beach, FL
- Comprehensive Hematology Oncology (ONare Alliance, LLC / Exigent Research, LLC · St. Petersburg, FL
Illinois · 1
- Illinois Cancer Care · Peoria, IL
Louisiana · 1
- Louisiana State University · New Orleans, LA
Michigan · 1
- Trinity Health-Michigan · Ypsilanti, MI
Nebraska · 1
- Nebraska Methodist · Omaha, NE
New York · 1
- Stony Brook University Cancer Center · Stony Brook, NY
Oregon · 1
- Oregon Oncology Specialists · Salem, OR
Pennsylvania · 1
- Cancer Care Associates of York · York, PA
Texas · 1
- The University of Texas MD Anderson Cancer Center · Houston, TX
Washington · 1
- Cancer Care Northwest · Spokane, WA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.