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A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

NCT06226883

This study is recruiting at 23 US sites in 13 states, according to its ClinicalTrials.gov record last updated .

Summary

This is a Phase 2, randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety of 3 active dose regimens of MORF-057 in adult study participants with moderately to severely active Crohn's disease (CD).

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Inflammatory Bowel Diseases
  • Crohn's Disease

Eligibility basics and study details

Study type
Interventional
Phase
Phase 2
Ages
18 to 85 years
Sex
All
Healthy volunteers
Not accepted
Sponsor
Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)
Last updated on ClinicalTrials.gov
October 8, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

California · 2

  • Gastro Care Institute · Lancaster, CA
  • Infinity Clinical Research · San Diego, CA

Colorado · 1

  • Peak Gastroenterology Associates - Colorado Springs · Colorado Springs, CO

Florida · 4

  • Clinical Research of Osceola · Kissimmee, FL
  • Bioresearch Partner-Kendale Lakes · Miami, FL
  • Endoscopic Research Inc · Orlando, FL
  • Tropical Clinical Trials · Palmetto Bay, FL

Georgia · 2

  • Atlanta Gastroenterology Associates (Part of United Digestive) · Atlanta, GA
  • Atlanta Gastroenterology Specialists, PC · Atlanta, GA

Louisiana · 1

  • Tandem Clinical Research · Houma, LA

Missouri · 1

  • SSM Health DePaul Hospital- St. Louis · Bridgeton, MO

Nevada · 1

  • Las Vegas Clinical Trials · North Las Vegas, NV

North Carolina · 2

  • Cross Creek Medical Clinic · Fayetteville, NC
  • Peters Medical Research · High Point, NC

South Carolina · 1

  • Palmetto Gastroenterology Clinical Research · Summerville, SC

Tennessee · 1

  • Gastrointestinal Associates of Northeast Tennessee · Johnson City, TN

Texas · 5

  • GI Alliance - Cedar Park · Cedar Park, TX
  • The University of Texas Health Science Center at Houston · Houston, TX
  • Prime Clinical Research - Lewisville · Lewisville, TX
  • Prime Clinical Research · Mansfield, TX
  • Tyler Research Institute, LLC · Tyler, TX

Utah · 1

  • Care Access Research - Ogden · Ogden, UT

Virginia · 1

  • Gastroenterology Associates of Central Virginia · Lynchburg, VA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.