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A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

NCT06131840

This study is recruiting at 19 US sites in 11 states, according to its ClinicalTrials.gov record last updated .

Summary

This clinical trial is studying advanced solid tumors. Solid tumors are cancers that start in a part of your body like your lungs or liver instead of your blood. Once tumors have grown bigger in one place but haven't spread, they're called locally advanced. If your cancer has spread to other parts of your body, it's called metastatic. When a cancer has gotten so big it can't easily be removed or has spread to other parts of the body, it is called unresectable. These types of cancer are harder to treat.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Colorectal Neoplasms
  • Carcinoma, Non-Small-Cell Lung
  • Stomach Neoplasms
  • Pancreatic Ductal Adenocarcinoma
  • Gastroesophageal Junction Adenocarcinoma
  • Small Cell Lung Carcinoma

Eligibility basics and study details

Study type
Interventional
Phase
Phase 1
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
Seagen, a wholly owned subsidiary of Pfizer
Last updated on ClinicalTrials.gov
July 22, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Arizona · 2

  • Mayo Clinic Hospital · Phoenix, AZ
  • Mayo Clinic · Scottsdale, AZ

California · 2

  • City of Hope (City of Hope National Medical Center, City of Hope Medical Center) · Duarte, CA
  • IP Address: City of Hope Investigational Drug Services(IDS) · Duarte, CA

Colorado · 2

  • University of Colorado Hospital · Aurora, CO
  • University of Colorado Hospital - Anschutz Cancer Pavilion (ACP) · Aurora, CO

Florida · 2

  • Florida Cancer Specialists · Orlando, FL
  • Sarah Cannon Research Institute at Florida Cancer Specialists · Orlando, FL

Maryland · 1

  • Sidney Kimmel Comprehensive Cancer at Johns Hopkins · Baltimore, MD

Massachusetts · 1

  • Beth Israel Deaconess Medical Center · Boston, MA

Michigan · 1

  • START Midwest · Grand Rapids, MI

Minnesota · 2

  • Mayo Clinic · Rochester, MN
  • Mayo Clinic Cancer Center · Rochester, MN

Tennessee · 2

  • Sarah Cannon Research Institute - Pharmacy · Nashville, TN
  • SCRI Oncology Partners · Nashville, TN

Texas · 2

  • The University of Texas MD Anderson Cancer Center · Houston, TX
  • South Texas Accelerated Research Therapeutics, LLC · San Antonio, TX

Utah · 2

  • START Mountain Region · Salt Lake City, UT
  • South Texas Accelerated Research Therapeutics Mountain Region · West Valley City, UT

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.