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A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

NCT06129864

This study is recruiting at 45 US sites in 24 states, according to its ClinicalTrials.gov record last updated .

Summary

The main purpose of this study is to assess the efficacy and safety of volrustomig compared to observation in participants with unresected locally advanced head and neck squamous cell carcinoma (LA-HNSCC) who have not progressed after receiving definitive concurrent chemoradiotherapy (cCRT).

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Locally Advanced Head and Neck Squamous Cell Carcinoma

Eligibility basics and study details

Study type
Interventional
Phase
Phase 3
Ages
18 to 130 years
Sex
All
Healthy volunteers
Not accepted
Sponsor
AstraZeneca
Last updated on ClinicalTrials.gov
September 30, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Alabama · 1

  • Research Site · Birmingham, AL

Arizona · 1

  • Research Site · Phoenix, AZ

California · 4

  • Research Site · Fountain Valley, CA
  • Research Site · Los Angeles, CA
  • Research Site · Santa Rosa, CA
  • Research Site · Whittier, CA

Colorado · 3

  • Research Site · Aurora, CO
  • Research Site · Colorado Springs, CO
  • Research Site · Lone Tree, CO

District of Columbia · 1

  • Research Site · Washington D.C., DC

Florida · 3

  • Research Site · Fort Myers, FL
  • Research Site · Palm Bay, FL
  • Research Site · West Palm Beach, FL

Illinois · 1

  • Research Site · Niles, IL

Iowa · 1

  • Research Site · Des Moines, IA

Kentucky · 1

  • Research Site · Louisville, KY

Louisiana · 1

  • Research Site · Baton Rouge, LA

Maryland · 5

  • Research Site · Baltimore, MD
  • Research Site · Bethesda, MD
  • Research Site · Hyattsville, MD
  • Research Site · Towson, MD
  • Research Site · Upper Marlboro, MD

Massachusetts · 2

  • Research Site · Boston, MA
  • Research Site · Fairhaven, MA

Michigan · 1

  • Research Site · Ann Arbor, MI

Minnesota · 1

  • Research Site · Minneapolis, MN

Missouri · 1

  • Research Site · St Louis, MO

New Jersey · 1

  • Research Site · Hackensack, NJ

New York · 3

  • Research Site · New York, NY
  • Research Site · New York, NY
  • Research Site · Stony Brook, NY

North Carolina · 2

  • Research Site · Charlotte, NC
  • Research Site · Winston-Salem, NC

Pennsylvania · 2

  • Research Site · Pittsburgh, PA
  • Research Site · York, PA

South Dakota · 2

  • Research Site · Sioux Falls, SD
  • Research Site · Sioux Falls, SD

Tennessee · 1

  • Research Site · Nashville, TN

Texas · 3

  • Research Site · Austin, TX
  • Research Site · Dallas, TX
  • Research Site · Odessa, TX

Utah · 2

  • Research Site · Salt Lake City, UT
  • Research Site · West Jordan, UT

Virginia · 2

  • Research Site · Fairfax, VA
  • Research Site · Norfolk, VA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.