Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
NCT06072612
This study is recruiting at 79 US sites in 21 states, according to its ClinicalTrials.gov record last updated .
Summary
This is a multicenter randomized, open label study to evaluate overall survival with the Bria-IMT regimen in combination with Checkpoint Inhibitor [Retifanlimab], versus Treatment of Patients'/Physicians' Choice (TPC) in advanced metastatic or locally recurrent breast cancer (aMBC) patients with no approved alternative therapies available.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Breast Cancer
- Metastatic Breast Cancer
- Breast Neoplasm
- Breast Cancer Metastatic
- End Stage Cancer
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 3
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- BriaCell Therapeutics Corporation
- Last updated on ClinicalTrials.gov
- September 2, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Arizona · 2
- Mayo Clinic-Comprehensive Cancer Center-Breast Clinic · Phoenix, AZ
- University of Arizona-Cancer Center · Tucson, AZ
California · 23
- Los Angeles cancer Network_Anaheim · Anaheim, CA
- Comprehensive Blood and Cancer Center · Bakersfield, CA
- Cedars-Sinai Cancer Beverly Hills · Beverly Hills, CA
- Los Angeles Cancer Network_Corona · Corona, CA
- Los Angeles cancer Network_Fountain Vallley · Fountain Valley, CA
- Los Angeles Cancer Network_Glendale · Glendale, CA
- Hoag Hospital Center · Irvine, CA
- Hoag Hospital Irvine · Irvine, CA
- Cedars-Sinai Cancer at Cedars-Sinai Medical Facility · Los Angeles, CA
- Los Angeles Cancer Network · Los Angeles, CA
- Los Angeles Cancer Network_Century City · Los Angeles, CA
- UCLA-Hematology/Oncology Medical Plaza · Los Angeles, CA
- UCLA-Hematology/Oncology_LA · Los Angeles, CA
- UCLA-Hematology/Oncology_LA 2 · Los Angeles, CA
- Los Angeles Cancer Network_Pasadena · Pasadena, CA
- Los Angeles cancer Network_Riverside · Riverside, CA
- UC San Diego · San Diego, CA
- St. John's Cancer Center · Santa Monica, CA
- UCLA-Department of Medicine Hematology/Oncology-Parkside · Santa Monica, CA
- UCLA-Hetamtology/Oncology_S Monica · Santa Monica, CA
- Torrance Memorial Cancer Center · Torrance, CA
- Los Angeles Cancer Network_Valley Pres · Van Nuys, CA
- Cedars-Sinai Breast Health Services Building · West Hollywood, CA
Connecticut · 1
- Smilow Cancer Hospital at Yale New Haven · New Haven, CT
Florida · 10
- University of Miami _SCCC - Aventura · Aventura, FL
- University of Miami-SCCC-Lennar · Coral Gables, FL
- University of Miami_SCCC-Coral Springs · Coral Springs, FL
- University of Miami Hospital and Clinics - Deerfield Beach · Deerfield Beach, FL
- University of Miami_SCCC-Hollywood · Hollywood, FL
- Mayo Clinic Florida-Comprehensive Cancer Center · Jacksonville, FL
- University of Miami_SCCC - Kendall · Miami, FL
- University Of Miami-SCCC-Miami · Miami, FL
- Advent Health - Orlando · Orlando, FL
- University of Miami-SCCC-Plantation · Plantation, FL
Georgia · 1
- Winship Cancer Institute of Emory University · Atlanta, GA
Illinois · 3
- Northwestern University · Chicago, IL
- Southern Illinois University-Simmons · Springfield, IL
- Carle Foundation Cancer Institute-Urbana · Urbana, IL
Indiana · 1
- Northwest Cancer Center · Dyer, IN
Kansas · 1
- AMR Kansas City Oncology · Kansas City, KS
Louisiana · 1
- Care Access-Marrero · Marrero, LA
Maryland · 1
- The Center for Cancer and Blood Disorders a division of American Oncology Partners, P.A. · Bethesda, MD
Minnesota · 1
- Mayo Clinic-Comprehensive Cancer Center-Breast Clinic · Rochester, MN
Nebraska · 1
- Nebraska Cancer Specialists · Omaha, NE
New Hampshire · 1
- Dartmouth Hitchcock Medical Center · Lebanon, NH
New Jersey · 1
- Hunterdon Medical Center · Flemington, NJ
New York · 11
- New York Cancer and Blood Specialists_North Shore Hematology Oncology Assocaites P.C. (Babylon) · Babylon, NY
- NYU Langone's Perlmutter Cancer Center · Manhattan, NY
- New York Cancer and Blood Specialists_North Shore Hematology Oncology Assocaites P.C.(New Hyde Park) · New Hyde Park, NY
- Manhattan Hematology /Oncology Associates · New York, NY
- New York Cancer and Blood Specialists_North Shore Hematology Oncology Assocaites P.C (NY) · New York, NY
- New York Cancers & Blood Specialists_North Shore Hematology Oncology Assocaites P.C (Patchogue) · Patchogue, NY
- New York Cancer and Blood Specialists_North Shore Hematology Oncology Assocaites P.C. (Port Jefferson Station2) · Port Jefferson Station, NY
- New York Cancer and Blood Specialists_North Shore Hematology Oncology Assocaites P.C.(Port Jefferson Station1) · Port Jefferson Station, NY
- New York Cancers & Blood Specialists · Port Jefferson Station, NY
- New York Cancer and Blood Specialists_North Shore Hematology Oncology Assocaites P.C. (Riverhead) · Riverhead, NY
- New York Cancer and Blood Specialists_North Shore Hematology Oncology Assocaites P.C (Brox) · The Bronx, NY
North Carolina · 1
- Regional Medical Oncology Center_Wlson · Wilson, NC
Ohio · 2
- Gabrail Cancer & Research Center · Canton, OH
- Cleveland Clinic · Cleveland, OH
Texas · 12
- Mary Crowley Cancer Research · Dallas, TX
- Texas Oncology-Baylor Charles A. Sammons Cancer Center · Dallas, TX
- DHR Health Oncology Institute · Edinburg, TX
- Texas Oncology - Fredericksburg · Fredericksburg, TX
- Texas Oncology - Harlingen · Harlingen, TX
- Texas Oncology McAllen · McAllen, TX
- Texas Oncology, New Braunfels · New Braunfels, TX
- Texas Oncology - San Antonio Northeast · San Antonio, TX
- Texas Oncology - San Antonio Stone Oak · San Antonio, TX
- Texas Oncology-San Antonio Cancer Care · San Antonio, TX
- Tranquil Clinical Research · Webster, TX
- Texas Oncology - Weslaco · Weslaco, TX
Virginia · 1
- Hematology-Oncology Associates of Fredericksburg, Inc · Fredericksburg, VA
Washington · 3
- Cancer Care Northwest_2 (605 E. Holland) · Spokane, WA
- Cancer Care Northwest-1 (601 S. Sherman) · Spokane, WA
- Cancer Care Northwest · Spokane Valley, WA
Wisconsin · 1
- Sheboygan Cancer & Blood Specialists · Sheboygan, WI
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.