Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis
NCT06051617
This study is recruiting at 54 US sites in 23 states, according to its ClinicalTrials.gov record last updated .
Summary
The goal of this clinical study is to learn more about the study drug, seladelpar, and its effects on clinical outcomes in participants with primary biliary cholangitis (PBC) and compensated cirrhosis. The primary objective of this study is to evaluate the effect of seladelpar compared to placebo on EFS. EFS is defined as the time from start of treatment to the first occurrence of any of the following adjudicated events up to Week 156.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Primary Biliary Cholangitis
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 3
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Gilead Sciences
- Last updated on ClinicalTrials.gov
- October 6, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alabama · 1
- University of Alabama at Birmingham · Birmingham, AL
Arizona · 1
- St. Joseph's Hospital and Medical Center - 350 W. Thomas · Phoenix, AZ
California · 10
- OM Research LLC · Lancaster, CA
- Cedar Sinai Medical Center · Los Angeles, CA
- SCPMG/Kaiser Permanente Los Angeles Medical Center · Los Angeles, CA
- California Liver Research Institute · Pasadena, CA
- Stanford University · Redwood City, CA
- Kaiser Roseville · Roseville, CA
- University of California, Davis Medical Center · Sacramento, CA
- California Pacific Medical Center - Sutter Pacific Medical Foundation · San Francisco, CA
- Connie Frank Transplant Center at UCSF · San Francisco, CA
- Kaiser Permanente - South San Francisco Medical Center · South San Francisco, CA
Florida · 4
- Covenant Metabolic Specialists, LLC · Fort Myers, FL
- Schiff Center for Liver Diseases/University of Miami · Miami, FL
- Covenant Metabolic Specialists, LLC · Sarasota, FL
- Florida Research Institute · Tampa, FL
Georgia · 1
- Piedmont Atlanta Hospital / Piedmont Transplant Institute · Atlanta, GA
Illinois · 2
- Northwestern University · Chicago, IL
- University of Chicago Medical Center · Chicago, IL
Iowa · 1
- University Of Iowa Hospitals And Clinics · Iowa City, IA
Kentucky · 1
- University of Louisville, Clinical Trials Unit · Louisville, KY
Louisiana · 2
- Ochsner Clinic Foundation · Jefferson, LA
- University Health System - East Jefferson General Hospital Campus · New Orleans, LA
Maryland · 2
- Mercy Medical Center · Baltimore, MD
- Walter Reed National Military · Bethesda, MD
Massachusetts · 2
- Beth Israel Deaconess Medical Center · Boston, MA
- Massachusetts General Hospital · Boston, MA
Michigan · 1
- Henry Ford Medical Center - Columbus · Detroit, MI
Minnesota · 2
- Mayo Clinic · Rochester, MN
- University of Rochester Medical Center - Strong Memorial Hospital · Rochester, MN
New York · 4
- Northwell Health Center for Liver Disease and Transplantation · Manhasset, NY
- Mount Sinai · New York, NY
- New York-Presbyterian/Weill Cornell Medical Center · New York, NY
- NYU Langone Health · New York, NY
North Carolina · 1
- Wake Forest Baptist Medical Center · Winston-Salem, NC
Ohio · 3
- The Cleveland Clinic Foundation · Cleveland, OH
- University Hosptials Cleveland Medical Center · Cleveland, OH
- The Ohio State University Medical Center · Columbus, OH
Pennsylvania · 4
- Penn State Health Milton S. Hershey Medical Center · Hershey, PA
- Thomas Jefferson University · Philadelphia, PA
- University of Pennsylvania Perelman Center for Advanced Medicine · Philadelphia, PA
- UPMC Center for Liver Diseases · Pittsburgh, PA
South Carolina · 1
- Medical University of South Carolina · Charleston, SC
Tennessee · 1
- Gastro One · Cordova, TN
Texas · 5
- The Liver Institute at Methodist Dallas Medical Center · Dallas, TX
- University of Texas Southwestern Medical Center, Professional Office Building One · Dallas, TX
- Soma Clinical Trials · Denison, TX
- American Research Corporation · San Antonio, TX
- Pinnacle Clinical Research, PLLC · San Antonio, TX
Virginia · 3
- MedStar Health Research Institute / MedStar Georgetown Transplant Institute at Fairfax · Fairfax, VA
- Maryview Hospital LLC d/b/a Bon Secours Liver Institute of Hampton Roads · Newport News, VA
- VCU Health Clinical Research Services Unit (CRSU) · Richmond, VA
Washington · 1
- Liver Institute Northwest · Seattle, WA
Wisconsin · 1
- Medical College of Wisconsin - 8701 Watertown Plan · Milwaukee, WI
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.