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The Effects of Successful OSA Treatment on Memory and AD Biomarkers in Older Adults Study

NCT05988385

This study is recruiting at 4 US sites in 3 states, according to its ClinicalTrials.gov record last updated .

Summary

The Effects of Successful OSA TreatmENT on Memory and AD BIomarkers in Older AduLts (ESSENTIAL) study is a 5-year, multicenter randomized open-label trial that will screen 400 cognitively normal older adults recruited from well-established sleep clinics at 4 academic medical centers, with newly diagnosed moderate-severe OSA.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Obstructive Sleep Apnea
  • Cognitive Decline

Eligibility basics and study details

Study type
Interventional
Phase
Not applicable
Ages
55 to 85 years
Sex
All
Healthy volunteers
Not accepted
Sponsor
California Pacific Medical Center Research Institute
Last updated on ClinicalTrials.gov
August 6, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Arizona · 1

  • University of Arizona · Tucson, AZ

New York · 2

  • Mount Sinai · New York, NY
  • New York University · New York, NY

Pennsylvania · 1

  • University of Pittsburgh · Pittsburgh, PA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.