Cough Capture as a Portal Into the Lung

Summary

The lung is a privileged organ; blood does not reflect most lung processes well, if at all. Therefore, for population scale diagnostics, the investigator team is developing non-invasive portals to the lung, for eventual early detection/risk assessment and diagnostic purposes. However, large macromolecules are not likely suspended nor readily detected in the breath. In particular, genomic DNA in the breath condensate (EBC) is very sparse, and where present, generally highly fragmented, not readily amenable to sequencing based assessments of DNA somatic mutation burden or distribution.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

• Lung Diseases
• Lung Cancer
• Lung Diseases, Obstructive
• Lung Diseases, Interstitial
• Lung Inflammation

Eligibility basics and study details

Study type

Observational

Phase

Not applicable

Ages

21 years and older

Sex

All

Healthy volunteers

Not accepted

Sponsor

Albert Einstein College of Medicine

Last updated on ClinicalTrials.gov

January 13, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites