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Non-invasive Vagal Nerve Stimulation in Opioid Use Disorders UH3

NCT05834478

This study is recruiting at 5 US sites in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

This study is being done to answer the question: what is the effect of Vagal Nerve Stimulation (VNS) dosing on opioid withdrawal responses in individuals with a history of Opioid Use Disorders (OUDs)? Eligible participants will be in the study for one week in an inpatient research hospital stay, have an MRI scan, and have a follow-up call 1-3 months after their inpatient stay. Participants will complete several psychiatric questionnaires/interviews, physiological monitoring with several devices, brain imaging, and VNS testing.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Withdrawal Symptoms
  • Opioid Use Disorder
  • Opioid Use

Eligibility basics and study details

Study type
Interventional
Phase
Phase 3
Ages
18 to 75 years
Sex
All
Healthy volunteers
Not accepted
Sponsor
Emory University
Last updated on ClinicalTrials.gov
March 27, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Georgia · 5

  • 12 Executive Park Drive · Atlanta, GA
  • Emory University · Atlanta, GA
  • Emory University Clinical Research Network · Atlanta, GA
  • Georgia Institute of Technology · Atlanta, GA
  • Rollins School of Public Health · Atlanta, GA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.