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Anti-Inflammatory Challenge in Schizophrenia

NCT05823532

This study is recruiting at 2 US sites in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

This study aims to illuminate the biological underpinnings of negative symptoms in schizophrenia-particularly motivational impairments-by probing the link between systemic inflammation and neural activity in reward-related brain circuits. The primary goal of this study is to determine: Ventral Striatum Activation: Assess how reward anticipation engages the ventral striatum in individuals with schizophrenia, both before and after an anti-inflammatory intervention.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Schizophrenia

Eligibility basics and study details

Study type
Interventional
Phase
Phase 4
Ages
18 to 55 years
Sex
All
Healthy volunteers
Not accepted
Sponsor
Emory University
Last updated on ClinicalTrials.gov
June 3, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Georgia · 2

  • Emory University Hospital · Atlanta, GA
  • Grady Memorial Hospital · Atlanta, GA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.