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Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors

NCT05797168

This study is recruiting at 10 US sites in 9 states, according to its ClinicalTrials.gov record last updated .

Summary

This research is designed to determine if experimental treatment with Antibody-drug conjugate, AZD5335, alone, or in combination with anti-cancer agents is safe, tolerable, and has anti-cancer activity in patients with advanced tumors

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Ovarian Cancer
  • Lung Adenocarcinoma
  • Endometrial Cancer
  • Lung Squamous Cell Carcinoma

Eligibility basics and study details

Study type
Interventional
Phase
Phase 1/2
Ages
18 to 130 years
Sex
All
Healthy volunteers
Not accepted
Sponsor
AstraZeneca
Last updated on ClinicalTrials.gov
October 5, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

California · 2

  • Research Site · Duarte, CA
  • Research Site · Irvine, CA

Colorado · 1

  • Research Site · Aurora, CO

Massachusetts · 1

  • Research Site · Boston, MA

Michigan · 1

  • Research Site · Detroit, MI

Ohio · 1

  • Research Site · Columbus, OH

Oregon · 1

  • Research Site · Portland, OR

Rhode Island · 1

  • Research Site · Providence, RI

Texas · 1

  • Research Site · Houston, TX

Virginia · 1

  • Research Site · Fairfax, VA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.