Neutrophil and Monocyte Deactivation Via the SeLective CytopheretIc Device - A Randomized Clinical Trial in Acute Kidney Injury
NCT05758077
This study is recruiting at 21 US sites in 12 states, according to its ClinicalTrials.gov record last updated .
Summary
This randomized, controlled, pivotal study is intended to determine whether up to ten sequential 24-hour treatments with the Selective Cytopheretic Device (SCD) will improve survival in patients with Acute Kidney Injury (AKI) requiring continuous kidney replacement therapy (CKRT) when compared to CKRT alone (standard of care). This study is further intended to determine whether SCD therapy will reduce the duration of maintenance dialysis secondary to AKI. This study will enroll approximately 339 subjects across 30 US sites.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Acute Kidney Injury
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Not applicable
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- SeaStar Medical
- Last updated on ClinicalTrials.gov
- September 10, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alabama · 1
- University of Alabama Birmingham Hospital · Birmingham, AL
California · 3
- Ronald Reagan UCLA Medical Center · Los Angeles, CA
- Stanford University · Palo Alto, CA
- University of California San Francisco · San Francisco, CA
Florida · 1
- AdventHealth Orlando · Orlando, FL
Georgia · 1
- Emory Healthcare · Atlanta, GA
Iowa · 1
- University of Iowa Hospital · Iowa City, IA
Louisiana · 1
- Ochsner LSU Health Academic Medical Center · Shreveport, LA
Michigan · 2
- University of Michigan · Ann Arbor, MI
- Henry Ford Medical Center · Detroit, MI
Minnesota · 1
- Mayo Clinic · Rochester, MN
Ohio · 2
- University of Cincinnati · Cincinnati, OH
- Cleveland Clinic · Cleveland, OH
Pennsylvania · 2
- St Luke's University Hospital · Bethlehem, PA
- Saint Mary Medical Center · Langhorne, PA
Texas · 5
- University of Texas Southwestern Medical Center · Dallas, TX
- Brooke Army Medical Center · Fort Sam Houston, TX
- Methodist Hospital · San Antonio, TX
- Methodist Hospital Metropolitan · San Antonio, TX
- University of Texas Health San Antonio · San Antonio, TX
Virginia · 1
- Sentara Health · Norfolk, VA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.