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Study of Tucatinib and Doxil in Participants With Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Metastatic Breast Cancer

NCT05748834

This study is recruiting at 7 US sites in 5 states, according to its ClinicalTrials.gov record last updated .

Summary

This clinical trial is evaluating tucatinib in combination with Doxil in participants with human epidermal growth factor 2 positive (HER2+) locally advanced or metastatic breast cancer. The main goals of this study are to: Learn how well the combination of tucatinib and Doxil works Learn more about the side effects of the combination of tucatinib and Doxil

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Breast Cancer

Eligibility basics and study details

Study type
Interventional
Phase
Phase 2
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
SCRI Development Innovations, LLC
Last updated on ClinicalTrials.gov
March 20, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Maryland · 1

  • Maryland Oncology Hematology · Columbia, MD

Pennsylvania · 1

  • Alliance Cancer Specialists · Bensalem, PA

Tennessee · 1

  • SCRI Oncology Partners · Nashville, TN

Texas · 2

  • Texas Oncology- DFW · Dallas, TX
  • Texas Oncology- San Antonio · San Antonio, TX

Virginia · 2

  • Virginia Oncology Associates · Norfolk, VA
  • Blue Ridge Cancer Care (Oncology & Hematology Assoc of SW Virginia, Inc) · Salem, VA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.