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Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia

NCT05741853

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

Difficulties with speech and language are the first and most notable symptoms of primary progressive aphasia (PPA). While there is evidence that demonstrates positive effects of speech-language treatment for individuals with PPA who only speak one language (monolinguals), there is a significant need for investigating the effects of treatment that is optimized for bilingual speakers with PPA. This stage 2 efficacy clinical trial seeks to establish the effects of culturally and linguistically tailored speech-language interventions administered to bilingual individuals with PPA.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Primary Progressive Aphasia
  • Dementia
  • Dementia, Frontotemporal
  • Alzheimer Disease
  • Neurodegenerative Diseases
  • Frontotemporal Lobar Degeneration
  • Apraxia, Motor
  • Dysarthria
  • Communication Disorders
  • Language Disorders
  • Speech Disorders
  • Neurocognitive Disorders
  • Aphasia
  • Bilingual Aphasia

Eligibility basics and study details

Study type
Interventional
Phase
Not applicable
Ages
40 years and older
Sex
All
Healthy volunteers
Accepted
Sponsor
Stephanie Grasso
Last updated on ClinicalTrials.gov
June 10, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Texas · 1

  • University of Texas at Austin · Austin, TX

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.