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Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

NCT05712200

This study is recruiting at 131 US sites in 30 states, according to its ClinicalTrials.gov record last updated .

Summary

A study to evaluate the effect of abelacimab relative to placebo on the rate of ischemic stroke or systemic embolism (SE) in patients with Atrial Fibrillation (AF) who have been deemed by their responsible physicians or by their own decision to be unsuitable for oral anticoagulation therapy.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Atrial Fibrillation (AF)

Eligibility basics and study details

Study type
Interventional
Phase
Phase 3
Ages
65 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
Anthos Therapeutics, Inc.
Last updated on ClinicalTrials.gov
July 13, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Alabama · 3

  • Anthos Investigational site 9939 · Birmingham, AL
  • Anthos Investigative Site 1040 · Birmingham, AL
  • Anthos Investigative Site 1041 · Mobile, AL

Arizona · 3

  • Anthos Investigative Site 1099 · Peoria, AZ
  • Anthos Investigative Site 9906 · Phoenix, AZ
  • Anthos Investigative Site 9927 · Yuma, AZ

California · 10

  • Anthos Investigative Site 9929 · Huntington Beach, CA
  • Anthos Investigative Site 9959 · Imperial, CA
  • Anthos Investigative Site 9921 · Lancaster, CA
  • Anthos Investigative Site 1078 · Loma Linda, CA
  • Anthos Investigative Site 1077 · Los Angeles, CA
  • Anthos Investigational site 9821 · Orange, CA
  • Anthos Investigative Site 1071 · San Dimas, CA
  • Anthos Investigative Site 9938 · Santa Rosa, CA
  • Anthos Investigative Site 9908 · South Gate, CA
  • Anthos Investigative Site 9907 · Vista, CA

Colorado · 2

  • Anthos Investigative Site 1095 · Aurora, CO
  • Anthos Investigative Site 9922 · Golden, CO

Connecticut · 1

  • Anthos Investigative Site 1012 · Stamford, CT

Florida · 27

  • Anthos Investigative Site 9934 · Altamonte Springs, FL
  • Anthos Investigative Site 1013 · Boca Raton, FL
  • Anthos Investigational site 9810 · Bradenton, FL
  • Anthos Investigational site 9818 · Clearwater, FL
  • Anthos Investigative Site 1022 · Clearwater, FL
  • Anthos Investigative Site 1025 · Clearwater, FL
  • Anthos Investigative Site 1019 · Daytona Beach, FL
  • Anthos Investigative Site 9936 · Hialeah, FL
  • Anthos Investigative Site 1083 · Hollywood, FL
  • Anthos Investigative Site 9804 · Hollywood, FL
  • Anthos Investigational site 9808 · Jacksonville, FL
  • Anthos Investigational site 9813 · Jacksonville, FL
  • Anthos Investigational site 9828 · Jacksonville, FL
  • Anthos Investigative Site 9904 · Lake Mary, FL
  • Anthos Investigative Site 1093 · Lutz, FL
  • Anthos Investigative Site 9933 · Miami, FL
  • Anthos Investigational site 9823 · Miami Lakes, FL
  • Anthos Investigative Site 9940 · Ocala, FL
  • Anthos Investigative Site 9944 · Ocala, FL
  • Anthis Investigational site 9811 · Pensacola, FL
  • Anthos Investigational site9830 · Pensacola, FL
  • Anthos Investigative Site 1026 · Safety Harbor, FL
  • Anthos Investigative Site 1002 · Saint Augustine, FL
  • Anthos Investigative Site 1004 · Saint Augustine, FL
  • Anthos Investigative Site 1044 · Tamarac, FL
  • Anthos Investigative Site 1088 · Tamarac, FL
  • Anthos Investigative Site 9911 · The Villages, FL

Georgia · 3

  • Anthos Investigative Site 1033 · Macon, GA
  • Anthos Investigative Site 1003 · Suwanee, GA
  • Anthos Investigative Site 9953 · Tucker, GA

Illinois · 3

  • Anthos Investigative Site 1030 · Park Ridge, IL
  • Anthos Investigative Site 9932 · Rockford, IL
  • Anthos Investigative Site 9925 · Winfield, IL

Indiana · 2

  • Anthos Investigative Site 9915 · Evansville, IN
  • Anthos Investigative Site 1098 · Merrillville, IN

Iowa · 1

  • Anthos Investigative Site 9956 · West Des Moines, IA

Kansas · 2

  • Anthos Investigative Site 9958 · Hutchinson, KS
  • Anthos Investigative Site 1016 · Wichita, KS

Louisiana · 3

  • Anthos Investigational site 9968 · Eunice, LA
  • Anthos Investigative Site 1043 · Shreveport, LA
  • Anthos Investigational site 9803 · West Monroe, LA

Maine · 1

  • Anthos Investigative Site 1054 · Bangor, ME

Maryland · 7

  • Anthos Investigational site 9961 · Baltimore, MD
  • Anthos Investigational site 9965 · Baltimore, MD
  • Anthos Investigative Site 1039 · Baltimore, MD
  • Anthos Investigative Site 9957 · Baltimore, MD
  • Anthos Investigative Site 1023 · Lanham, MD
  • Anthos Investigational site 9962 · Rockville, MD
  • Anthos Investigational site 9969 · Salisbury, MD

Massachusetts · 2

  • Anthos Investigative Site 9918 · Boston, MA
  • Anthos Investigational site 9812 · Fall River, MA

Michigan · 4

  • Anthos Investigational site 9819 · Lansing, MI
  • Anthos Investigative Site 1021 · Lansing, MI
  • Anthos Investigative Site 9946 · Petoskey, MI
  • Anthos Investigative Site 1059 · Southgate, MI

Missouri · 3

  • Anthos Investigative Site 9948 · Kansas City, MO
  • Anthos Investigational site 9825 · St Louis, MO
  • Anthos Investigational site 9966 · St Louis, MO

Nevada · 1

  • Anthos Investigative Site 9914 · Las Vegas, NV

New Jersey · 3

  • Anthos Investigational Site 9807 · Elmer, NJ
  • Anthos Investigational site 9801 · Sewell, NJ
  • Anthos Investigational site 9963 · Somerset, NJ

New York · 6

  • Anthos Investigative Site 9931 · Albany, NY
  • Anthos Investigative Site 9905 · Brooklyn, NY
  • Anthos Investigational site 9829 · Hauppauge, NY
  • Anthos Investigative Site 1037 · Rosedale, NY
  • Anthos Investigative Site 9935 · Stony Brook, NY
  • Anthos Investigative Site 9920 · Valhalla, NY

North Carolina · 5

  • Anthos Investigative Site 1005 · Charlotte, NC
  • Anthos Investigative Site 9912 · Durham, NC
  • Anthos Investigative Site 9950 · Pinehurst, NC
  • Anthos Investigative Site 9951 · Statesville, NC
  • Anthos Investigative Site 9952 · Wilmington, NC

Ohio · 2

  • Anthos Investigative Site 9902 · Beavercreek, OH
  • Anthos Investigative Site 9945 · Dayton, OH

Oklahoma · 1

  • Anthos Investigative Site 9917 · Oklahoma City, OK

Oregon · 1

  • Anthos Investigative Site 1075 · Portland, OR

Pennsylvania · 1

  • Anthos Investigative Site 1087 · Horsham, PA

South Carolina · 1

  • Anthos Investigational site 9814 · Fort Mill, SC

Tennessee · 3

  • Anthos Investigational site 9954 · Chattanooga, TN
  • Anthos Investigative Site 9941 · Jefferson City, TN
  • Anthos Investigative Site 1056 · Memphis, TN

Texas · 23

  • Anthos Investigative Site 9928 · Allen, TX
  • Anthos Investigative Site 9913 · Beaumont, TX
  • Anthos Investigational site 9967 · Bryan, TX
  • Anthos Investigative Site 9942 · Dallas, TX
  • Anthos Investigative Site 9943 · Dallas, TX
  • Anthos Investigative Site 1091 · El Paso, TX
  • Anthos Investigative Site 9930 · Greenville, TX
  • Anthos Investigative Site 1064 · Houston, TX
  • Anthos Investigative Site 1068 · Houston, TX
  • Anthos Investigative Site 1097 · Houston, TX
  • Anthos Investigative Site 9903 · Houston, TX
  • Anthos Investigational site 9833 · Humble, TX
  • Anthos Investigative Site 1063 · McAllen, TX
  • Anthos Investigative Site 1079 · McKinney, TX
  • Anthos Investigative Site 1096 · McKinney, TX
  • Anthos Investigative Site 1024 · Odessa, TX
  • Anthos Investigative Site 1085 · Port Arthur, TX
  • Anthos Investigative Site 9923 · Sherman, TX
  • Anthos Investigative Site 9916 · Tyler, TX
  • Anthos Investigative Site 9910 · Victoria, TX
  • Anthos Investigative Site 1060 · Waco, TX
  • Anthos Investigative Site 9909 · Webster, TX
  • Anthos Investigative Site 1092 · Wylie, TX

Virginia · 4

  • Anthos Investigative Site 1018 · Falls Church, VA
  • Anthos Investigational site 9817 · Fredericksburg, VA
  • Anthos Investigative Site 1009 · Roanoke, VA
  • Anthos Investigative Site 9949 · Vienna, VA

Washington · 3

  • Anthos Investigational site 9826 · Puyallup, WA
  • Anthos Investigative Site 9926 · Redmond, WA
  • Anthos Investigative Site 1073 · Tacoma, WA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.