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APOL1 Genetic Testing in African Americans

NCT05656261

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

Recent breakthroughs in medical genetics have discovered that a portion of kidney failure affecting the Black community is mediated by coding variants in a gene called apolipoprotein L1 (APOL1) - and that genetic variants, not race - account for increased risk. For APOL1 genetic testing to be applied in a manner that improves patient care and outcomes, more information is needed regarding associations of genotype with clinical parameters related to kidney health.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Genetic Predisposition
  • Chronic Kidney Diseases
  • Nephropathy
  • APOL1 Associated Kidney Disease
  • Disparities

Eligibility basics and study details

Study type
Observational
Phase
Not applicable
Ages
18 to 90 years
Sex
All
Healthy volunteers
Accepted
Sponsor
St. Louis University
Last updated on ClinicalTrials.gov
March 20, 2025

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Missouri · 1

  • SSM Health Saint Louis University Hospital · St Louis, MO

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.