Comparison of Breast Cancer Screening With CESM to DBT in Women With Dense Breasts
NCT05625659
This study is recruiting at 11 US sites in 10 states, according to its ClinicalTrials.gov record last updated .
Summary
The over-arching goal of the Contrast-Enhanced Spectral Mammography Imaging Screening Trial (CMIST) is to determine if dual-energy contrast-enhanced spectral mammography (CESM) can detect more cancers with fewer false positives than digital breast tomosynthesis (DBT) in women with dense breasts. Aim 1: To evaluate the performance of CESM compared to DBT at baseline for breast-cancer screening in women with dense breasts. Aim 2: To evaluate the performance of CESM compared to DBT at the 1-year follow up for breast-cancer screening in women with dense breasts.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Breast Cancer
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Not applicable
- Ages
- 45 to 74 years
- Sex
- Female
- Healthy volunteers
- Accepted
- Sponsor
- American College of Radiology
- Last updated on ClinicalTrials.gov
- July 31, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alabama · 1
- University of Alabama, Birmingham · Birmingham, AL
Florida · 1
- Boca Raton Regional Hospital - Christine E. Lynn Women's Health and Wellness Institute · Boca Raton, FL
Massachusetts · 2
- Massachusetts General Hospital · Boston, MA
- Boston Breast Diagnostic Center · Wellesley Hills, MA
Michigan · 1
- Henry Ford Health · Detroit, MI
New Jersey · 1
- Thomas Jefferson University · Sewell, NJ
New York · 1
- Memorial Sloan Kettering Cancer Center · New York, NY
North Carolina · 1
- Carolina Breast Imaging Specialists · Greenville, NC
Pennsylvania · 1
- Thomas Jefferson University Hospital · Philadelphia, PA
Texas · 1
- The University of Texas MD Anderson Cancer Center · Houston, TX
Virginia · 1
- University of Virginia · Charlottesville, VA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.